5LSW

A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin

Summary for 5LSW

Entry DOI	10.2210/pdb5lsw/pdb
Descriptor	Cell differentiation protein RCD1 homolog, LD12033p, SULFATE ION, ... (5 entities in total)
Functional Keywords	gene regulation, deadenylation, ccr4-not, translational repression, translation
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus : Q92600
Total number of polymer chains	4
Total formula weight	67328.10
Authors	Sgromo, A.,Raisch, T.,Bawankar, P.,Bhandari, D.,Chen, Y.,Kuzuoglu-Ozturk, D.,Weichenrieder, O.,Izaurralde, E. (deposition date: 2016-09-05, release date: 2017-02-15, Last modification date: 2024-01-17)
Primary citation	Sgromo, A.,Raisch, T.,Bawankar, P.,Bhandari, D.,Chen, Y.,Kuzuoglu-Ozturk, D.,Weichenrieder, O.,Izaurralde, E. A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin. Nat Commun, 8:14307-14307, 2017 Cited by PubMed: 28165457 DOI: 10.1038/ncomms14307 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation