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5U4R
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BU of 5u4r by Molmil
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 53-1A09 Fab.
Descriptor: VRC 315 53-1A09 Fab Heavy chain, VRC 315 53-1A09 Fab Light chain
Authors:Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D.
Deposit date:2016-12-05
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans.
Sci Immunol, 2, 2017
6MGL
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BU of 6mgl by Molmil
Crystal structure of the catalytic domain from GH74 enzyme PoGH74 from Paenibacillus odorifer, D60A mutant in complex with XXLG and XGXXLG xyloglucan
Descriptor: 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Stogios, P.J, Skarina, T, Arnal, G, Watanabe, N, Brumer, H, Savchenko, A.
Deposit date:2018-09-14
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74endo-xyloglucanase.
Biochem. J., 475, 2018
6NCL
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BU of 6ncl by Molmil
Near-atomic structure of icosahedrally averaged PBCV-1 capsid
Descriptor: Major capsid protein, P1, P10, ...
Authors:Fang, Q, Rossmann, M.G.
Deposit date:2018-12-11
Release date:2019-01-30
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic structure of a giant virus.
Nat Commun, 10, 2019
8W4L
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BU of 8w4l by Molmil
Crystal structure of closed conformation of human immunoglobulin Fc in presence of EndoSz
Descriptor: CHLORIDE ION, Immunoglobulin gamma-1 heavy chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guan, H.H, Lin, C.C, Hsieh, Y.C, Chen, C.J.
Deposit date:2023-08-24
Release date:2024-07-03
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based High-Efficiency Homogeneous Antibody Platform by Endoglycosidase Sz Provides Insights into Its Transglycosylation Mechanism.
Jacs Au, 4, 2024
8XQB
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BU of 8xqb by Molmil
Mature virion portal vertex of bacteriophage lambda
Descriptor: Capsid decoration protein, Head completion protein, Head-tail connector protein FII, ...
Authors:Wang, J.W, Gu, Z.W.
Deposit date:2024-01-05
Release date:2024-04-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural morphing in the viral portal vertex of bacteriophage lambda.
J.Virol., 98, 2024
5UE5
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BU of 5ue5 by Molmil
proMMP-7 with heparin octasaccharide bound to the catalytic domain
Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, Matrilysin, ...
Authors:Fulcher, Y.G, Prior, S.H, Linhardt, R.J, Van Doren, S.R.
Deposit date:2016-12-29
Release date:2017-07-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7.
Structure, 25, 2017
5UTF
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BU of 5utf by Molmil
Crystal Structure of a Stabilized DS-SOSIP.6mut BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, Y177W, N300M, N302M, T320L, I420M in Complex with Human Antibodies PGT122 and 35O22 at 4.3 A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Heavy chain, ...
Authors:Pancera, M, Chuang, G.-Y, Xu, K, Kwong, P.D.
Deposit date:2017-02-14
Release date:2017-03-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.
J. Virol., 91, 2017
5V7J
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BU of 5v7j by Molmil
Crystal Structure at 3.7 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Four Glycans (N197, N276, N362, and N462) removed in Complex with Neutralizing Antibodies 3H+109L and 35O22.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 35O22 Fab heavy chain, ...
Authors:Stewart-Jones, G.B.E, Zhou, T, Kwong, P.D.
Deposit date:2017-03-20
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.
Cell Rep, 19, 2017
5TIP
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BU of 5tip by Molmil
The Structure of the Major Capsid protein of PBCV-1
Descriptor: 6-deoxy-2,3-di-O-methyl-alpha-L-mannopyranose-(1-2)-beta-L-rhamnopyranose-(1-4)-beta-D-xylopyranose-(1-4)-[alpha-D-mannopyranose-(1-3)-alpha-D-rhamnopyranose-(1-3)][alpha-D-galactopyranose-(1-2)]alpha-L-fucopyranose-(1-3)-[beta-D-xylopyranose-(1-4)]beta-D-glucopyranose, MERCURY (II) ION, Major capsid protein, ...
Authors:Klose, T, De Castro, C, Speciale, I, Molinaro, A, Van Etten, J.L, Rossmann, M.G.
Deposit date:2016-10-03
Release date:2017-10-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the chlorovirus PBCV-1 major capsid glycoprotein determined by combining crystallographic and carbohydrate molecular modeling approaches.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5V4E
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BU of 5v4e by Molmil
Engineered human IgG Fc domain glyco801 (Fc801)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, W, Marshall, N, Zhang, Y.J.
Deposit date:2017-03-09
Release date:2017-06-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.216 Å)
Cite:IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
7Q15
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BU of 7q15 by Molmil
Crystal structure of FcRn and beta-2-microglobulin in complex with IgG1-Fc-MST-HN (efgartigimod)
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, IgG1-Fc-MST-HN, ...
Authors:Pannecoucke, E, Savvides, S.N.
Deposit date:2021-10-18
Release date:2022-09-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.
Nat Commun, 13, 2022
6OKP
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BU of 6okp by Molmil
B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074
Descriptor: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6Q1G
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BU of 6q1g by Molmil
Human antibody H1244 of the human antibody lineage 652
Descriptor: GLYCEROL, H1244 Fab heavy chain, H1244 Fab lambda chain
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-04
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q1E
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BU of 6q1e by Molmil
Inferred precursor (UCA) of the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda chain
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q9E
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BU of 6q9e by Molmil
Complex III2 focused refinement from Ovine respiratory supercomplex I+III2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CARDIOLIPIN, Cytochrome b, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-18
Release date:2019-08-21
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6Q0H
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BU of 6q0h by Molmil
Inferred intermediate I-7 (I-7-0) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-01
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q18
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BU of 6q18 by Molmil
Human antibody H1244 in complex with the influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, H1244 Fab heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-03
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6QBX
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BU of 6qbx by Molmil
Ovine respiratory supercomplex I+III2 closed class.
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-24
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6Q19
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BU of 6q19 by Molmil
Inferred intermediate (I-6) of the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda chain
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q1J
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BU of 6q1j by Molmil
Antibody H2227 from the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda light chain
Authors:McCarthy, K.R, Harrison, S.C, Raymond, D.D.
Deposit date:2019-08-05
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6QC4
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BU of 6qc4 by Molmil
Ovine respiratory supercomplex I+III2 open class 3
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein, Cytochrome b, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-26
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6Q1A
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BU of 6q1a by Molmil
Inferred intermediate mutant (I-6V) of the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda chain, GLYCEROL
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-03
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q0L
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BU of 6q0l by Molmil
Inferred intermediate I-7 (I-7-1) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-01
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q0I
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BU of 6q0i by Molmil
Inferred intermediate I-7 (I-7-6) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-01
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q1K
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BU of 6q1k by Molmil
Inferred intermediate I-7 of the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda light chain, GLYCEROL
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-05
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019

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