5U4R
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 53-1A09 Fab.
Summary for 5U4R
Entry DOI | 10.2210/pdb5u4r/pdb |
Descriptor | VRC 315 53-1A09 Fab Heavy chain, VRC 315 53-1A09 Fab Light chain (3 entities in total) |
Functional Keywords | immune system, antibody, influenza, human vaccine trial |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 97074.20 |
Authors | Joyce, M.G.,Andrews, S.F.,Mascola, J.R.,McDermott, A.B.,Kwong, P.D. (deposition date: 2016-12-05, release date: 2017-11-15, Last modification date: 2023-10-04) |
Primary citation | Andrews, S.F.,Joyce, M.G.,Chambers, M.J.,Gillespie, R.A.,Kanekiyo, M.,Leung, K.,Yang, E.S.,Tsybovsky, Y.,Wheatley, A.K.,Crank, M.C.,Boyington, J.C.,Prabhakaran, M.S.,Narpala, S.R.,Chen, X.,Bailer, R.T.,Chen, G.,Coates, E.,Kwong, P.D.,Koup, R.A.,Mascola, J.R.,Graham, B.S.,Ledgerwood, J.E.,McDermott, A.B. Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2:-, 2017 Cited by PubMed: 28783708DOI: 10.1126/sciimmunol.aan2676 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.762 Å) |
Structure validation
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