5U4R

Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 53-1A09 Fab.

Summary for 5U4R

Entry DOI	10.2210/pdb5u4r/pdb
Descriptor	VRC 315 53-1A09 Fab Heavy chain, VRC 315 53-1A09 Fab Light chain (3 entities in total)
Functional Keywords	immune system, antibody, influenza, human vaccine trial
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	97074.20
Authors	Joyce, M.G.,Andrews, S.F.,Mascola, J.R.,McDermott, A.B.,Kwong, P.D. (deposition date: 2016-12-05, release date: 2017-11-15, Last modification date: 2023-10-04)
Primary citation	Andrews, S.F.,Joyce, M.G.,Chambers, M.J.,Gillespie, R.A.,Kanekiyo, M.,Leung, K.,Yang, E.S.,Tsybovsky, Y.,Wheatley, A.K.,Crank, M.C.,Boyington, J.C.,Prabhakaran, M.S.,Narpala, S.R.,Chen, X.,Bailer, R.T.,Chen, G.,Coates, E.,Kwong, P.D.,Koup, R.A.,Mascola, J.R.,Graham, B.S.,Ledgerwood, J.E.,McDermott, A.B. Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2:-, 2017 Cited by PubMed: 28783708 DOI: 10.1126/sciimmunol.aan2676 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.762 Å)

Structure validation