5UE5
proMMP-7 with heparin octasaccharide bound to the catalytic domain
Summary for 5UE5
Entry DOI | 10.2210/pdb5ue5/pdb |
Related | 2MZE 5UE2 |
NMR Information | BMRB: 25485 |
Descriptor | Matrilysin, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | glycan complex with protein, enzyme complex with heparin oligosaccharide, zymogen, allosteric effector site, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30128.01 |
Authors | Fulcher, Y.G.,Prior, S.H.,Linhardt, R.J.,Van Doren, S.R. (deposition date: 2016-12-29, release date: 2017-07-19, Last modification date: 2024-05-01) |
Primary citation | Fulcher, Y.G.,Prior, S.H.,Masuko, S.,Li, L.,Pu, D.,Zhang, F.,Linhardt, R.J.,Van Doren, S.R. Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7. Structure, 25:1100-1110.e5, 2017 Cited by PubMed: 28648610DOI: 10.1016/j.str.2017.05.019 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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