3B9S
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![BU of 3b9s by Molmil](/molmil-images/mine/3b9s) | Macrophage Migration Inhibitory Factor (MIF) complexed with Inhibitor, 4-IPP. | Descriptor: | 4-phenylpyrimidine, GLYCEROL, Macrophage Migration Inhibitory Factor, ... | Authors: | Zierow, S, Crichlow, G, Lolis, E. | Deposit date: | 2007-11-06 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Res., 68, 2008
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3B3X
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![BU of 3b3x by Molmil](/molmil-images/mine/3b3x) | Crystal structure of class A beta-lactamase of Bacillus licheniformis BS3 with aminocitrate | Descriptor: | 2-(carboxymethyl)-D-aspartic acid, Beta-lactamase | Authors: | Sauvage, E, Herman, R, Kerff, F, Charlier, P. | Deposit date: | 2007-10-23 | Release date: | 2007-11-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis Bioorg.Med.Chem.Lett., 18, 2008
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3BE1
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![BU of 3be1 by Molmil](/molmil-images/mine/3be1) | Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Fragment-Heavy Chain, ... | Authors: | Bostrom, J.M, Wiesmann, C, Appleton, B.A. | Deposit date: | 2007-11-15 | Release date: | 2008-11-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site Science, 323, 2009
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3BFT
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![BU of 3bft by Molmil](/molmil-images/mine/3bft) | Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution | Descriptor: | (2S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid, CACODYLATE ION, CHLORIDE ION, ... | Authors: | Beich-Frandsen, M, Mirza, O, Vestergaard, B, Gajhede, M, Kastrup, J.S. | Deposit date: | 2007-11-23 | Release date: | 2008-10-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51, 2008
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3B9Y
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![BU of 3b9y by Molmil](/molmil-images/mine/3b9y) | Crystal structure of the Nitrosomonas europaea Rh protein | Descriptor: | Ammonium transporter family Rh-like protein, UNKNOWN LIGAND, octyl beta-D-glucopyranoside | Authors: | Li, X, Jayachandran, S, Nguyen, H.-H.T, Chan, M.K. | Deposit date: | 2007-11-07 | Release date: | 2007-12-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the Nitrosomonas europaea Rh protein. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3BGK
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![BU of 3bgk by Molmil](/molmil-images/mine/3bgk) | |
3SO5
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![BU of 3so5 by Molmil](/molmil-images/mine/3so5) | |
3S5T
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![BU of 3s5t by Molmil](/molmil-images/mine/3s5t) | |
3S3B
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![BU of 3s3b by Molmil](/molmil-images/mine/3s3b) | Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization | Descriptor: | COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... | Authors: | Luna, V.M, Fee, J.A, Deniz, A.A, Stout, C.D. | Deposit date: | 2011-05-18 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. Biochemistry, 51, 2012
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3BIP
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![BU of 3bip by Molmil](/molmil-images/mine/3bip) | Crystal structure of yeast Spt16 N-terminal Domain | Descriptor: | FACT complex subunit SPT16 | Authors: | VanDemark, A.P, Xin, H, McCullough, L, Rawlins, R, Bentley, S, Heroux, A, David, S.J, Hill, C.P, Formosa, T. | Deposit date: | 2007-11-30 | Release date: | 2007-12-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits. J.Biol.Chem., 283, 2008
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3BEQ
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![BU of 3beq by Molmil](/molmil-images/mine/3beq) | Neuraminidase of A/Brevig Mission/1/1918 H1N1 strain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Xu, X, Zhu, X, Wilson, I.A. | Deposit date: | 2007-11-19 | Release date: | 2008-09-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural characterization of the 1918 influenza virus H1N1 neuraminidase J.Virol., 82, 2008
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3BJE
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![BU of 3bje by Molmil](/molmil-images/mine/3bje) | |
3BHV
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![BU of 3bhv by Molmil](/molmil-images/mine/3bhv) | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B | Descriptor: | 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, Cell division protein kinase 2, Cyclin-A2, ... | Authors: | Echalier, A, Bettayeb, K, Ferandin, Y, Lozach, O, Clement, M, Valette, A, Liger, F, Marquet, B, Morris, J.C, Endicott, J.A, Joseph, B, Meijer, L. | Deposit date: | 2007-11-29 | Release date: | 2008-02-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases Cancer Res., 67, 2007
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3BIM
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![BU of 3bim by Molmil](/molmil-images/mine/3bim) | |
3B2U
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![BU of 3b2u by Molmil](/molmil-images/mine/3b2u) | Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... | Authors: | Ferguson, K.M, Li, S, Kussie, P. | Deposit date: | 2007-10-19 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. Structure, 16, 2008
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3B5L
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![BU of 3b5l by Molmil](/molmil-images/mine/3b5l) | |
3B7N
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![BU of 3b7n by Molmil](/molmil-images/mine/3b7n) | Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylinositol | Descriptor: | (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ACETATE ION, PHOSPHATE ION, ... | Authors: | Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V. | Deposit date: | 2007-10-31 | Release date: | 2008-02-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily Mol.Cell, 29, 2008
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3B7U
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![BU of 3b7u by Molmil](/molmil-images/mine/3b7u) | Leukotriene A4 Hydrolase Complexed with KELatorphan | Descriptor: | ACETIC ACID, IMIDAZOLE, Leukotriene A-4 hydrolase, ... | Authors: | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | Deposit date: | 2007-10-31 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3B0U
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![BU of 3b0u by Molmil](/molmil-images/mine/3b0u) | tRNA-dihydrouridine synthase from Thermus thermophilus in complex with tRNA fragment | Descriptor: | FLAVIN MONONUCLEOTIDE, RNA (5'-R(*GP*GP*(H2U)P*A)-3'), tRNA-dihydrouridine synthase | Authors: | Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I. | Deposit date: | 2011-06-14 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Molecular basis of dihydrouridine formation on tRNA Proc.Natl.Acad.Sci.USA, 108, 2011
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3BGD
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![BU of 3bgd by Molmil](/molmil-images/mine/3bgd) | Thiopurine S-Methyltransferase | Descriptor: | 9H-purine-6-thiol, S-ADENOSYL-L-HOMOCYSTEINE, Thiopurine S-methyltransferase | Authors: | Peng, Y, Yee, V.C. | Deposit date: | 2007-11-26 | Release date: | 2008-06-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis of Substrate Recognition in Thiopurine S-Methyltransferase Biochemistry, 47 (23), 6216 6225, 2008. 10.1021/bi800102x, 2008
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3B24
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![BU of 3b24 by Molmil](/molmil-images/mine/3b24) | Hsp90 alpha N-terminal domain in complex with an aminotriazine fragment molecule | Descriptor: | 4-(ethylsulfanyl)-6-methyl-1,3,5-triazin-2-amine, Heat shock protein HSP 90-alpha, MAGNESIUM ION | Authors: | Fukami, T.A, Ono, N. | Deposit date: | 2011-07-21 | Release date: | 2011-09-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design Bioorg.Med.Chem.Lett., 21, 2011
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3B2M
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![BU of 3b2m by Molmil](/molmil-images/mine/3b2m) | |
3S39
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![BU of 3s39 by Molmil](/molmil-images/mine/3s39) | Structure of Thermus thermophilus cytochrome ba3 oxidase 60s after Xe depressurization | Descriptor: | COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... | Authors: | Luna, V.M, Fee, J.A, Deniz, A.A, Stout, C.D. | Deposit date: | 2011-05-17 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4.8 Å) | Cite: | Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. Biochemistry, 51, 2012
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3RER
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![BU of 3rer by Molmil](/molmil-images/mine/3rer) | Crystal structure of E. coli Hfq in complex with AU6A RNA and ADP | Descriptor: | 5'-R(*AP*UP*UP*UP*UP*UP*UP*A)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wang, W.W, Wu, J.H, Shi, Y.Y. | Deposit date: | 2011-04-05 | Release date: | 2011-10-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Cooperation of Escherichia coli Hfq hexamers in DsrA binding. Genes Dev., 25, 2011
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3R1B
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![BU of 3r1b by Molmil](/molmil-images/mine/3r1b) | Open crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene | Descriptor: | (4-tert-butylphenyl)acetaldehyde, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ... | Authors: | Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R. | Deposit date: | 2011-03-09 | Release date: | 2011-05-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity. Biochemistry, 50, 2011
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