Crystal structure of the BCL6 BTB domain dimer in complex with the BCOR BBD corepressor peptide

Summary for 3BIM

DescriptorB-cell lymphoma 6 protein, BCL-6 corepressor (3 entities in total)
Functional Keywordsprotein-peptide compex, activator, chromosomal rearrangement, dna-binding, metal-binding, nucleus, phosphoprotein, polymorphism, proto-oncogene, repressor, transcription, transcription regulation, zinc, zinc-finger, alternative splicing, ank repeat, chromatin regulator, disease mutation, transcription repressor
Biological sourceHomo sapiens (human)
Cellular locationNucleus  P41182 Q6W2J9
Total number of polymer chains16
Total molecular weight131903.61
Prive, G.G.,Ghetu, A.F. (deposition date: 2007-11-30, release date: 2008-01-08, Last modification date: 2017-10-25)
Primary citation
Ghetu, A.F.,Corcoran, C.M.,Cerchietti, L.,Bardwell, V.J.,Melnick, A.,Prive, G.G.
Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.
Mol.Cell, 29:384-391, 2008
PubMed: 18280243 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2007.12.026
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25716 1.3% 12.3% 6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25