3BIM

Crystal structure of the BCL6 BTB domain dimer in complex with the BCOR BBD corepressor peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, B, C, D, E...)	B-cell lymphoma 6 protein	polymer	127	14559.8	8	UniProt (P41182) Pfam (PF00651)	Homo sapiens (human)	BCL-6, Zinc finger protein 51, LAZ-3 protein, BCL-5, Zinc finger and BTB domain-containing protein 27
2	B, D, F, H, J... (I, J, K, L, M...)	BCL-6 corepressor	polymer	19	1928.1	8	UniProt (Q6W2J9)	Homo sapiens (human)	BCoR
3	AA, BA, CA, DA, EA... (F, N, G, O, H...)	water	water		18.0	141	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 5 - 129 (UniProt: P41182)

PDB	External Database	Details
Gly 3	-	expression tag
Ser 4	-	expression tag
Gln 8	Cys 8	engineered mutation
Arg 67	Cys 67	engineered mutation
Asn 84	Cys 84	engineered mutation

I, J, K, L, M, N, O, P: 498 - 514 (UniProt: Q6W2J9)

PDB	External Database	Details
Gly 496	-	expression tag
Ser 497	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	131903.6
All*	Total formula weight	131903.6

*Water molecules are not included.