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1YYO
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BU of 1yyo by Molmil
Crystal structure of RNase III mutant E110K from Aquifex aeolicus complexed with double-stranded RNA at 2.9-Angstrom Resolution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*G)-3', Ribonuclease III
Authors:Gan, J, Tropea, J.E, Austin, B.P, Court, D.L, Waugh, D.S, Ji, X.
Deposit date:2005-02-25
Release date:2005-11-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Intermediate states of ribonuclease III in complex with double-stranded RNA
Structure, 13, 2005
2NUE
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BU of 2nue by Molmil
Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 2.9-Angstrom Resolution
Descriptor: 46-MER, Ribonuclease III
Authors:Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X.
Deposit date:2006-11-09
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
9ASQ
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BU of 9asq by Molmil
Human Drosha, DGCR8 and SRSF3 in complex with Pri-let-7f1
Descriptor: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
Authors:Garg, A, Joshua-Tor, L.
Deposit date:2024-02-26
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:RNAi_protein_f1_SR
To Be Published
2QVW
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BU of 2qvw by Molmil
Structure of Giardia Dicer refined against twinned data
Descriptor: GLP_546_48378_50642, MANGANESE (II) ION
Authors:Doudna, J.A, MacRae, I.J.
Deposit date:2007-08-09
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer
Acta Crystallogr.,Sect.D, 63, 2007
7XW2
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BU of 7xw2 by Molmil
Cryo-EM structure of human DICER-pre-miRNA in a dicing state
Descriptor: CALCIUM ION, Endoribonuclease Dicer, RNA (73-MER)
Authors:Lee, H, Roh, S.-H.
Deposit date:2022-05-26
Release date:2023-03-08
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structure of the human DICER-pre-miRNA complex in a dicing state.
Nature, 615, 2023
8DFV
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BU of 8dfv by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIa
Descriptor: CALCIUM ION, Endoribonuclease Dcr-1, Loquacious, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-22
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
6TNN
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BU of 6tnn by Molmil
Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA
Descriptor: 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C.
Deposit date:2019-12-09
Release date:2020-09-30
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs.
Mol.Cell, 80, 2020
7VG2
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BU of 7vg2 by Molmil
Cryo-EM structure of Arabidopsis DCL3 in complex with a 40-bp RNA
Descriptor: CALCIUM ION, Dicer-like 3, TAS1a forward strand (5'-phosphorylation), ...
Authors:Wang, Q, Du, J.
Deposit date:2021-09-14
Release date:2021-10-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
7W0A
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BU of 7w0a by Molmil
dmDicer2-LoqsPD-dsRNA Dimer status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
9ASN
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BU of 9asn by Molmil
Human Drosha and DGCR8 in complex with Pri-miR-98
Descriptor: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
Authors:Garg, A, Joshua-Tor, L.
Deposit date:2024-02-26
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:RNAi_protein_98
To Be Published
9ASP
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BU of 9asp by Molmil
Human Drosha and DGCR8 in complex with Pri-let-7a1
Descriptor: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ...
Authors:Garg, A, Joshua-Tor, L.
Deposit date:2024-02-26
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:RNAi_protein_a1
To Be Published
3J6B
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BU of 3j6b by Molmil
Structure of the yeast mitochondrial large ribosomal subunit
Descriptor: 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ...
Authors:Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
5B16
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BU of 5b16 by Molmil
X-ray structure of DROSHA in complex with the C-terminal tail of DGCR8.
Descriptor: Microprocessor complex subunit DGCR8, Ribonuclease 3,DROSHA,Ribonuclease 3,DROSHA,Ribonuclease 3, ZINC ION
Authors:Kwon, S.C, Nguyen, T.A, Choi, Y.G, Jo, M.H, Hohng, S, Kim, V.N, Woo, J.S.
Deposit date:2015-11-23
Release date:2016-02-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Human DROSHA
Cell, 164, 2016
5MRC
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BU of 5mrc by Molmil
Structure of the yeast mitochondrial ribosome - Class A
Descriptor: 15S ribosomal RNA, 21S ribosomal RNA, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Desai, N, Brown, A, Amunts, A, Ramakrishnan, V.
Deposit date:2016-12-22
Release date:2017-02-15
Last modified:2018-02-07
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:The structure of the yeast mitochondrial ribosome.
Science, 355, 2017
8DG5
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BU of 8dg5 by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIb
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
7V6B
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BU of 7v6b by Molmil
Structure of the Dicer-2-R2D2 heterodimer
Descriptor: Dicer-2, isoform A, R2D2
Authors:Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O.
Deposit date:2021-08-20
Release date:2022-03-23
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
7V6C
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BU of 7v6c by Molmil
Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex
Descriptor: Dicer-2, isoform A, R2D2, ...
Authors:Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O.
Deposit date:2021-08-20
Release date:2022-03-23
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
8DG7
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BU of 8dg7 by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
7W0B
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BU of 7w0b by Molmil
Dicer2-LoqsPD complex at apo status
Descriptor: Dicer-2, isoform A, Loquacious, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2021-11-18
Release date:2022-04-27
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
2FFL
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BU of 2ffl by Molmil
Crystal Structure of Dicer from Giardia intestinalis
Descriptor: Dicer, MANGANESE (II) ION
Authors:Doudna, J.A, MacRae, I.J, Adams, P.D.
Deposit date:2005-12-19
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structural Basis of Double-Stranded RNA Processing by Dicer
Science, 311, 2006
8HF1
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BU of 8hf1 by Molmil
DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state
Descriptor: Dicer-2, isoform A, LD06392p, ...
Authors:Su, S, Wang, J, Ma, J.
Deposit date:2022-11-09
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
6V5B
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BU of 6v5b by Molmil
Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state
Descriptor: CALCIUM ION, Microprocessor complex subunit DGCR8, Pri-miR-16-2 (78-MER), ...
Authors:Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y.
Deposit date:2019-12-04
Release date:2020-04-08
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
Mol.Cell, 78, 2020
8HF0
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BU of 8hf0 by Molmil
DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state
Descriptor: Dicer-2, isoform A, LD06392p, ...
Authors:Su, S, Wang, J, Wang, H.W, Ma, J.
Deposit date:2022-11-09
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
8DGA
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BU of 8dga by Molmil
Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV
Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ...
Authors:Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A.
Deposit date:2022-06-23
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
7VG3
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BU of 7vg3 by Molmil
Cryo-EM structure of Arabidopsis DCL3 in complex with a 30-bp RNA
Descriptor: CALCIUM ION, Dicer-like 3, TAS1a RNA forward strand (5'-phosphorylated), ...
Authors:Wang, Q, Du, J.
Deposit date:2021-09-14
Release date:2021-10-27
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021

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