7XW2

Cryo-EM structure of human DICER-pre-miRNA in a dicing state

Summary for 7XW2

• Entry DOI: 10.2210/pdb7xw2/pdb
• EMDB information: 33489
• Descriptor: Endoribonuclease Dicer, RNA (73-MER), CALCIUM ION (3 entities in total)
• Functional Keywords: dicer, rnaseiii, rna-binding, micro-rna processing, gene regulation, gene regulation-rna complex, gene regulation/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 242371.27

Authors

Lee, H.,Roh, S.-H. (deposition date: 2022-05-26, release date: 2023-03-08, Last modification date: 2023-03-22)

• Primary citation: Lee, Y.Y.,Lee, H.,Kim, H.,Kim, V.N.,Roh, S.H.; Structure of the human DICER-pre-miRNA complex in a dicing state.; Nature, 615:331-338, 2023; PubMed: 36813958; DOI: 10.1038/s41586-023-05723-3

Experimental method

ELECTRON MICROSCOPY (3.04 Å)