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4D8D
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BU of 4d8d by Molmil
Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant
Descriptor: GLYCEROL, Protein Nef, Tyrosine-protein kinase Fyn
Authors:Arold, S.T, Hoh, F, Dumas, C.
Deposit date:2012-01-10
Release date:2013-01-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5201 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
6UY7
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BU of 6uy7 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R
Descriptor: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
6UY9
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BU of 6uy9 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S
Descriptor: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3, SODIUM ION
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
6UY8
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BU of 6uy8 by Molmil
Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SH3 and cysteine-rich domain-containing protein 3
Authors:Rufenach, B, Van Petegem, F.
Deposit date:2019-11-12
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Structure, 28, 2020
8JHK
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BU of 8jhk by Molmil
Cryo-EM structure of the DOCK5/ELMO1 complex, focused on one protomer
Descriptor: Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1
Authors:Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M.
Deposit date:2023-05-23
Release date:2024-05-29
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.76 Å)
Cite:RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.
J.Biol.Chem., 300, 2024
3REB
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BU of 3reb by Molmil
HIV-1 Nef protein in complex with engineered Hck-SH3 domain
Descriptor: Protein Nef, Tyrosine-protein kinase HCK
Authors:Schulte, A, Blankenfeldt, W, Geyer, M.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
PLoS ONE, 6, 2011
8IAH
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BU of 8iah by Molmil
Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State I, Global map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Li, N, Chen, S, Gao, N.
Deposit date:2023-02-08
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
3RBB
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BU of 3rbb by Molmil
HIV-1 NEF protein in complex with engineered HCK SH3 domain
Descriptor: 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK
Authors:Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M.
Deposit date:2011-03-29
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly.
Traffic, 12, 2011
3REA
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BU of 3rea by Molmil
HIV-1 Nef protein in complex with engineered Hck-SH3 domain
Descriptor: Protein Nef, Tyrosine-protein kinase HCK
Authors:Schulte, A, Blankenfeldt, W, Geyer, M.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
PLoS ONE, 6, 2011
2KNB
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BU of 2knb by Molmil
Solution NMR structure of the parkin Ubl domain in complex with the endophilin-A1 SH3 domain
Descriptor: E3 ubiquitin-protein ligase parkin, Endophilin-A1
Authors:Trempe, J, Guennadi, K, Edna, C.M, Kalle, G.
Deposit date:2009-08-20
Release date:2009-12-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
2XKX
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BU of 2xkx by Molmil
Single particle analysis of PSD-95 in negative stain
Descriptor: DISKS LARGE HOMOLOG 4
Authors:Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M.
Deposit date:2010-07-15
Release date:2011-07-20
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING
Cite:Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95
Biochim.Biophys.Acta, 1808, 2011
7CSP
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BU of 7csp by Molmil
Structure of Ephexin4 IDPSH
Descriptor: Rho guanine nucleotide exchange factor 16
Authors:Zhang, M, Lin, L, Wang, C, Zhu, J.
Deposit date:2020-08-15
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CSR
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BU of 7csr by Molmil
Structure of Ephexin4 R676L
Descriptor: Rho guanine nucleotide exchange factor 16
Authors:Zhang, M, Lin, L, Wang, C, Zhu, J.
Deposit date:2020-08-17
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CSO
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BU of 7cso by Molmil
Structure of Ephexin4 DH-PH-SH3
Descriptor: Rho guanine nucleotide exchange factor 16, SULFATE ION
Authors:Zhang, M, Lin, L, Wang, C, Zhu, J.
Deposit date:2020-08-15
Release date:2021-02-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Double inhibition and activation mechanisms of Ephexin family RhoGEFs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7D7S
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BU of 7d7s by Molmil
HIV-1 SF2 Nef in complex with the Fyn SH3 R96I mutant
Descriptor: Protein Nef, Tyrosine-protein kinase Fyn
Authors:Aldehaiman, A, Shahul Hamed, U.F, Arold, S.T.
Deposit date:2020-10-05
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
7UD6
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BU of 7ud6 by Molmil
Designed Enzyme SH3-588 (Catechol O-methyltransferase catalytic domain and Src homology 3 binding domain fusion)
Descriptor: POTASSIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Tyrosine-protein kinase Fyn,Catechol O-methyltransferase
Authors:Ongpipattanakul, C, Nair, S.K.
Deposit date:2022-03-18
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Designer installation of a substrate recruitment domain to tailor enzyme specificity.
Nat.Chem.Biol., 19, 2023
7DPA
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BU of 7dpa by Molmil
Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex
Descriptor: Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1
Authors:Kukimoto-Niino, M, Katsura, K, Kaushik, R, Ehara, H, Yokoyama, T, Uchikubo-Kamo, T, Mishima-Tsumagari, C, Yonemochi, M, Ikeda, M, Hanada, K, Zhang, K.Y.J, Shirouzu, M.
Deposit date:2020-12-18
Release date:2021-08-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex.
Sci Adv, 7, 2021
5YPR
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BU of 5ypr by Molmil
Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor
Descriptor: Disks large homolog 4, Synthesized GK inhibitor
Authors:Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M.
Deposit date:2017-11-02
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
6B25
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BU of 6b25 by Molmil
Crystal structure of human STAC1 Tandem SH3 Domains (288-402)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein
Authors:Wong King Yuen, S.M, Van Petegem, F.
Deposit date:2017-09-19
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4N78
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BU of 4n78 by Molmil
The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton
Descriptor: Abl interactor 2, CHLORIDE ION, Cytoplasmic FMR1-interacting protein 1, ...
Authors:Chen, Z.C.
Deposit date:2013-10-15
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton.
Cell(Cambridge,Mass.), 156, 2014
3EHQ
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BU of 3ehq by Molmil
Crystal Structure of Human Osteoclast Stimulating Factor
Descriptor: 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1
Authors:Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L.
Deposit date:2008-09-14
Release date:2009-08-04
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
3EHR
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BU of 3ehr by Molmil
Crystal Structure of Human Osteoclast Stimulating Factor
Descriptor: Osteoclast-stimulating factor 1
Authors:Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L.
Deposit date:2008-09-14
Release date:2009-08-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
4ORZ
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BU of 4orz by Molmil
HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain
Descriptor: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19
Authors:Geyer, M, Lulf, S.
Deposit date:2014-02-12
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody.
Retrovirology, 11, 2014
3NMZ
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BU of 3nmz by Molmil
Crystal structure of APC complexed with Asef
Descriptor: APC variant protein, Rho guanine nucleotide exchange factor 4
Authors:Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
Deposit date:2010-06-23
Release date:2011-07-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
8WEJ
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BU of 8wej by Molmil
Structure of human phagocyte NADPH oxidase in the activated state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
Authors:Chen, L, Liu, X.
Deposit date:2023-09-18
Release date:2024-01-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024

223532

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