2KNB

Solution NMR structure of the parkin Ubl domain in complex with the endophilin-A1 SH3 domain

Summary for 2KNB

• Entry DOI: 10.2210/pdb2knb/pdb
• NMR Information: BMRB: 16813
• Descriptor: E3 ubiquitin-protein ligase parkin, Endophilin-A1 (2 entities in total)
• Functional Keywords: ubl, sh3, parkin, endophilin, cell junction, cell membrane, cell projection, endoplasmic reticulum, ligase, membrane, metal-binding, nucleus, postsynaptic cell membrane, s-nitrosylation, synapse, ubl conjugation pathway, zinc-finger, endocytosis, lipid-binding, phosphoprotein, sh3 domain, protein binding
• Biological source: Rattus norvegicus (brown rat,rat,rats); More
• Cellular location: Nucleus (By similarity): Q9JK66; Cytoplasm: O35179
• Total number of polymer chains: 2
• Total formula weight: 17131.24

Authors

Trempe, J.,Guennadi, K.,Edna, C.M.,Kalle, G. (deposition date: 2009-08-20, release date: 2009-12-22, Last modification date: 2013-06-19)

• Primary citation: Trempe, J.F.,Chen, C.X.,Grenier, K.,Camacho, E.M.,Kozlov, G.,McPherson, P.S.,Gehring, K.,Fon, E.A.; SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.; Mol.Cell, 36:1034-1047, 2009; PubMed: 20064468; DOI: 10.1016/j.molcel.2009.11.021

Experimental method

SOLUTION NMR