4D8D
Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant
Summary for 4D8D
Entry DOI | 10.2210/pdb4d8d/pdb |
Related | 3H0F 3H0H 3H0I |
Descriptor | Tyrosine-protein kinase Fyn, Protein Nef, GLYCEROL, ... (4 entities in total) |
Functional Keywords | signaling molecules, transferase-protein binding complex, transferase/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P06241 Host cell membrane ; Lipid-anchor ; Cytoplasmic side : P03406 |
Total number of polymer chains | 4 |
Total formula weight | 48533.96 |
Authors | Arold, S.T.,Hoh, F.,Dumas, C. (deposition date: 2012-01-10, release date: 2013-01-16, Last modification date: 2023-09-13) |
Primary citation | Aldehaiman, A.,Momin, A.A.,Restouin, A.,Wang, L.,Shi, X.,Aljedani, S.,Opi, S.,Lugari, A.,Shahul Hameed, U.F.,Ponchon, L.,Morelli, X.,Huang, M.,Dumas, C.,Collette, Y.,Arold, S.T. Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478:1525-1545, 2021 Cited by PubMed: 33787846DOI: 10.1042/BCJ20201002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5201 Å) |
Structure validation
Download full validation report