8JHK
Cryo-EM structure of the DOCK5/ELMO1 complex, focused on one protomer
Summary for 8JHK
Entry DOI | 10.2210/pdb8jhk/pdb |
EMDB information | 36271 |
Descriptor | Engulfment and cell motility protein 1, Dedicator of cytokinesis protein 5 (2 entities in total) |
Functional Keywords | elmo, dock, gef, gtpase, rho, rac, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 467321.97 |
Authors | Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M. (deposition date: 2023-05-23, release date: 2024-05-29, Last modification date: 2024-06-26) |
Primary citation | Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M. RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., :107459-107459, 2024 Cited by PubMed: 38857861DOI: 10.1016/j.jbc.2024.107459 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.76 Å) |
Structure validation
Download full validation report