8IIB
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![BU of 8iib by Molmil](/molmil-images/mine/8iib) | Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546) | Descriptor: | CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Fang, X, Lu, G, Hou, C, Gong, P. | Deposit date: | 2023-02-24 | Release date: | 2023-06-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virol Sin, 38, 2023
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4IKA
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![BU of 4ika by Molmil](/molmil-images/mine/4ika) | Crystal structure of EV71 3Dpol-VPg | Descriptor: | 3Dpol, NICKEL (II) ION, VPg | Authors: | Chen, C, Wang, Y.X, Lou, Z.Y. | Deposit date: | 2012-12-25 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: implication for a trans mechanism of VPg uridylylation J.Virol., 87, 2013
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2UUW
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![BU of 2uuw by Molmil](/molmil-images/mine/2uuw) | 2.75 angstrom structure of the D347G D348G mutant structure of Sapporo Virus RdRp Polymerase | Descriptor: | RNA-DIRECTED RNA POLYMERASE | Authors: | Fullerton, S, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P, Rohayem, J. | Deposit date: | 2007-03-07 | Release date: | 2007-05-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | The 2.76 Angstrom Resolution Structure of the D347G D348G Mutant Structure of Sapporo Virus Rdrp Polymerase To be Published
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3SFG
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![BU of 3sfg by Molmil](/molmil-images/mine/3sfg) | |
2WK4
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![BU of 2wk4 by Molmil](/molmil-images/mine/2wk4) | Dimeric structure of D347G D348G mutant of the sapporovirus RNA dependent RNA polymerase | Descriptor: | GLYCEROL, PROTEASE-POLYMERASE P70 | Authors: | Fullerton, S.W.B, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P.A, Rohayem, J. | Deposit date: | 2009-06-05 | Release date: | 2010-09-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Dimeric Structure of D347G D348G Mutant of the Sapporovirus Sapporovirus RNA Dependent RNA Polymerase To be Published
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5JXS
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![BU of 5jxs by Molmil](/molmil-images/mine/5jxs) | |
4IQX
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![BU of 4iqx by Molmil](/molmil-images/mine/4iqx) | Mutant P44S P169S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | Descriptor: | 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3') | Authors: | Ferrer-Orta, C, Verdaguer, N, Agudo, R, Perez-Luque, R. | Deposit date: | 2013-01-14 | Release date: | 2013-02-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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1KHW
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![BU of 1khw by Molmil](/molmil-images/mine/1khw) | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+ | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | Deposit date: | 2001-12-01 | Release date: | 2002-01-16 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
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5I61
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![BU of 5i61 by Molmil](/molmil-images/mine/5i61) | |
1HI0
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![BU of 1hi0 by Molmil](/molmil-images/mine/1hi0) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-31 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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3H5Y
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![BU of 3h5y by Molmil](/molmil-images/mine/3h5y) | Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2 | Descriptor: | 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | Deposit date: | 2009-04-22 | Release date: | 2009-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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3H5X
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![BU of 3h5x by Molmil](/molmil-images/mine/3h5x) | Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase | Descriptor: | 2'-amino-2'-deoxycytidine 5'-(tetrahydrogen triphosphate), 5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3', 5'-R(P*UP*GP*CP*CP*CP*GP*GP*GP*C)-3', ... | Authors: | Zamyatkin, D.F, Parra, F, Machin, A, Grochulski, P, Ng, K.K.S. | Deposit date: | 2009-04-22 | Release date: | 2009-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Binding of 2'-amino-2'-deoxycytidine-5'-triphosphate to norovirus polymerase induces rearrangement of the active site. J.Mol.Biol., 390, 2009
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4K4Y
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![BU of 4k4y by Molmil](/molmil-images/mine/4k4y) | Coxsackievirus B3 polymerase elongation complex (r2+1_form) | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*(DOC))-3'), ... | Authors: | Gong, P, Peersen, O.B. | Deposit date: | 2013-04-12 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
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4ZP8
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![BU of 4zp8 by Molmil](/molmil-images/mine/4zp8) | Coxsackievirus B3 Polymerase - F364L mutant | Descriptor: | RNA-dependent RNA polymerase | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.894 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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4ZPA
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![BU of 4zpa by Molmil](/molmil-images/mine/4zpa) | Coxsackievirus B3 Polymerase - F364Y mutant | Descriptor: | RNA-directed RNA polymerase, SULFATE ION | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.665 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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4ZP6
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![BU of 4zp6 by Molmil](/molmil-images/mine/4zp6) | Coxsackievirus B3 Polymerase - F364A mutant | Descriptor: | Genome polyprotein, SULFATE ION | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.648 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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4ZP9
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![BU of 4zp9 by Molmil](/molmil-images/mine/4zp9) | Coxsackievirus B3 Polymerase - F364I mutant | Descriptor: | RNA-dependent RNA polymerase | Authors: | Peersen, O.B, McDonald, S.M. | Deposit date: | 2015-05-07 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291, 2016
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3BSO
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![BU of 3bso by Molmil](/molmil-images/mine/3bso) | |
1HHT
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![BU of 1hht by Molmil](/molmil-images/mine/1hht) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | Descriptor: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-28 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HHS
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![BU of 1hhs by Molmil](/molmil-images/mine/1hhs) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2000-12-28 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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3BSN
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![BU of 3bsn by Molmil](/molmil-images/mine/3bsn) | |
1HI1
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![BU of 1hi1 by Molmil](/molmil-images/mine/1hi1) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-01 | Release date: | 2001-03-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1HI8
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![BU of 1hi8 by Molmil](/molmil-images/mine/1hi8) | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | Descriptor: | MAGNESIUM ION, P2 PROTEIN | Authors: | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | Deposit date: | 2001-01-03 | Release date: | 2001-03-27 | Last modified: | 2019-09-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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3CDU
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![BU of 3cdu by Molmil](/molmil-images/mine/3cdu) | Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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3CDW
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![BU of 3cdw by Molmil](/molmil-images/mine/3cdw) | Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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