4ZP6
Coxsackievirus B3 Polymerase - F364A mutant
Summary for 4ZP6
Entry DOI | 10.2210/pdb4zp6/pdb |
Descriptor | Genome polyprotein, SULFATE ION (3 entities in total) |
Functional Keywords | rna-dependent rna polymerase, transferase |
Biological source | Coxsackievirus B3 |
Cellular location | Host cytoplasm . Host cytoplasmic vesicle . Host cytoplasmic vesicle membrane . Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Virion : Q5UEA2 |
Total number of polymer chains | 1 |
Total formula weight | 53016.42 |
Authors | Peersen, O.B.,McDonald, S.M. (deposition date: 2015-05-07, release date: 2016-05-11, Last modification date: 2024-03-06) |
Primary citation | McDonald, S.,Block, A.,Beaucourt, S.,Moratorio, G.,Vignuzzi, M.,Peersen, O.B. Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo. J.Biol.Chem., 291:13999-14011, 2016 Cited by PubMed: 27137934DOI: 10.1074/jbc.M116.726596 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.648 Å) |
Structure validation
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