5KQR
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![BU of 5kqr by Molmil](/molmil-images/mine/5kqr) | Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine | Descriptor: | CHLORIDE ION, Methyltransferase, PHOSPHATE ION, ... | Authors: | Jain, R, Coloma, J, Rajashankar, K.R, Aggarwal, A.K. | Deposit date: | 2016-07-06 | Release date: | 2016-09-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.331 Å) | Cite: | Structures of NS5 Methyltransferase from Zika Virus. Cell Rep, 16, 2016
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6LD2
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![BU of 6ld2 by Molmil](/molmil-images/mine/6ld2) | Zika NS5 polymerase domain | Descriptor: | (1S,2S,4S,5R)-2,4-dimethoxy-5-thiophen-2-yl-cyclohexane-1-carboxylic acid, RNA-directed RNA polymerase NS5, ZINC ION | Authors: | El Sahili, A, Lescar, J. | Deposit date: | 2019-11-20 | Release date: | 2020-08-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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6LD1
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![BU of 6ld1 by Molmil](/molmil-images/mine/6ld1) | Zika NS5 polymerase domain | Descriptor: | 1,2-ETHANEDIOL, RNA-directed RNA polymerase NS5, ZINC ION | Authors: | El Sahili, A, Lescar, J. | Deposit date: | 2019-11-20 | Release date: | 2020-08-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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5KVG
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![BU of 5kvg by Molmil](/molmil-images/mine/5kvg) | Zika specific antibody, ZV-67, bound to ZIKA envelope DIII | Descriptor: | CHLORIDE ION, ZIKA Envelope DIII, ZV-67 Antibody Fab Heavy Chain, ... | Authors: | Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-07-14 | Release date: | 2016-08-03 | Last modified: | 2016-08-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016
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5KVF
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![BU of 5kvf by Molmil](/molmil-images/mine/5kvf) | Zika specific antibody, ZV-64, bound to ZIKA envelope DIII | Descriptor: | GLYCEROL, ZV-64 Antibody Fab Heavy Chain, ZV-64 Antibody Fab Light Chain, ... | Authors: | Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-07-14 | Release date: | 2016-08-03 | Last modified: | 2016-08-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016
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5KQS
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![BU of 5kqs by Molmil](/molmil-images/mine/5kqs) | Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine and 7-methyl-guanosine-5'-diphosphate | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, GLYCEROL, ... | Authors: | Coloma, J, Jain, R, Rajashankar, K.R, Aggarwal, A.K. | Deposit date: | 2016-07-06 | Release date: | 2016-09-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of NS5 Methyltransferase from Zika Virus. Cell Rep, 16, 2016
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6LD4
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![BU of 6ld4 by Molmil](/molmil-images/mine/6ld4) | Zika NS5 polymerase domain | Descriptor: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, 3-methoxybenzenesulfonamide, RNA-directed RNA polymerase NS5, ... | Authors: | El Sahili, A, Lescar, J. | Deposit date: | 2019-11-20 | Release date: | 2020-08-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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6S0J
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![BU of 6s0j by Molmil](/molmil-images/mine/6s0j) | Structure of Zika virus NS3 helicase in complex with ADP-MgF3(H2O)- | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... | Authors: | Ge, M, Molt Jr, R.W, Jenkins, H.T, Blackburn, G.M, Jin, Y, Antson, A.A. | Deposit date: | 2019-06-16 | Release date: | 2020-07-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor. Acs Catalysis, 11, 2021
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5ULP
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![BU of 5ulp by Molmil](/molmil-images/mine/5ulp) | Structure of the NS5 methyltransferase from Zika bound to MS2042 | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl][(4-fluorophenyl)methyl]amino}-5'-deoxyadenosine, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | Authors: | Jain, R, Aggarwal, A.K. | Deposit date: | 2017-01-25 | Release date: | 2017-05-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Development of a S-adenosylmethionine analog that intrudes the RNA-cap binding site of Zika methyltransferase. Sci Rep, 7, 2017
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5Y6N
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![BU of 5y6n by Molmil](/molmil-images/mine/5y6n) | Zika virus helicase in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Helicase domain from Genome polyprotein, MANGANESE (II) ION | Authors: | Yang, X.Y, Chen, C, Tian, H.L, Chi, H, Mu, Z.Y, Zhang, T.Q, Yang, K.L, Zhao, Q, Liu, X.H, Wang, Z.F, Ji, X.Y, Yang, H.T. | Deposit date: | 2017-08-12 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.571 Å) | Cite: | Mechanism of ATP hydrolysis by the Zika virus helicase. FASEB J., 32, 2018
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7M1V
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![BU of 7m1v by Molmil](/molmil-images/mine/7m1v) | Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation | Descriptor: | 1,2-ETHANEDIOL, 4-(2-{2,4-diamino-5-[2-(4-{[(2E)-1,3-thiazolidin-2-ylidene]sulfamoyl}phenyl)hydrazinyl]phenyl}hydrazinyl)-N-[(2S)-1,3-thiazolidin-2-yl]benzene-1-sulfonamide, CHLORIDE ION, ... | Authors: | Aleshin, A.E, Shiryaev, S.A, Liddington, R.C. | Deposit date: | 2021-03-15 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | To be provided To Be Published
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5KVD
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![BU of 5kvd by Molmil](/molmil-images/mine/5kvd) | Zika specific antibody, ZV-2, bound to ZIKA envelope DIII | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, ... | Authors: | Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-07-14 | Release date: | 2016-08-03 | Last modified: | 2016-08-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016
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6RWZ
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![BU of 6rwz by Molmil](/molmil-images/mine/6rwz) | Structure of Zika virus NS3 helicase in complex with ADP-BeF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MANGANESE (II) ION, ... | Authors: | Ge, M, Molt Jr, R.W, Jenkins, H.T, Blackburn, G.M, Jin, Y, Antson, A.A. | Deposit date: | 2019-06-07 | Release date: | 2020-07-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor. Acs Catalysis, 11, 2021
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5KVE
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![BU of 5kve by Molmil](/molmil-images/mine/5kve) | Zika specific antibody, ZV-48, bound to ZIKA envelope DIII | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Genome polyprotein, ... | Authors: | Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-07-14 | Release date: | 2016-08-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016
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5JMT
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![BU of 5jmt by Molmil](/molmil-images/mine/5jmt) | Crystal structure of Zika virus NS3 helicase | Descriptor: | NS3 helicase | Authors: | Tian, H, Ji, X, Yang, X, Xie, W, Yang, K, Chen, C, Wu, C, Chi, H, Mu, Z, Wang, Z, Yang, H. | Deposit date: | 2016-04-29 | Release date: | 2016-05-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.796 Å) | Cite: | The crystal structure of Zika virus helicase: basis for antiviral drug design Protein Cell, 7, 2016
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5MRK
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![BU of 5mrk by Molmil](/molmil-images/mine/5mrk) | |
6LD5
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![BU of 6ld5 by Molmil](/molmil-images/mine/6ld5) | Zika NS5 polymerase domain | Descriptor: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ... | Authors: | El Sahili, A, Lescar, J. | Deposit date: | 2019-11-20 | Release date: | 2020-08-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
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5NJV
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![BU of 5njv by Molmil](/molmil-images/mine/5njv) | Flavivirus NS5 domain | Descriptor: | CHLORIDE ION, NS5, S-ADENOSYLMETHIONINE | Authors: | Talapatra, S.K, Chatrin, C, Kozielski, F. | Deposit date: | 2017-03-29 | Release date: | 2018-01-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping. Oncotarget, 9, 2018
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5Y6M
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![BU of 5y6m by Molmil](/molmil-images/mine/5y6m) | Zika virus helicase in complex with ADP-AlF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Helicase domain from Genome polyprotein, ... | Authors: | Yang, X.Y, Chen, C, Tian, H.L, Chi, H, Mu, Z.Y, Zhang, T.Q, Yang, K.L, Zhao, Q, Liu, X.H, Wang, Z.F, Ji, X.Y, Yang, H.T. | Deposit date: | 2017-08-12 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Mechanism of ATP hydrolysis by the Zika virus helicase. FASEB J., 32, 2018
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5M5B
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![BU of 5m5b by Molmil](/molmil-images/mine/5m5b) | Crystal structure of Zika virus NS5 methyltransferase | Descriptor: | CHLORIDE ION, GLYCEROL, NS5 methyltransferase, ... | Authors: | Barral, K, Ortiz Lombardia, M, Coutard, B, Decroly, E, Lichiere, J. | Deposit date: | 2016-10-21 | Release date: | 2016-12-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives. J. Virol., 91, 2017
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5GOZ
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![BU of 5goz by Molmil](/molmil-images/mine/5goz) | |
7A3N
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![BU of 7a3n by Molmil](/molmil-images/mine/7a3n) | Crystal structure of Zika virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C10 | Descriptor: | CALCIUM ION, Core protein, EDE1 C10 Fab | Authors: | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A. | Deposit date: | 2020-08-18 | Release date: | 2021-12-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. Cell, 184, 2021
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5NJU
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![BU of 5nju by Molmil](/molmil-images/mine/5nju) | Flavivirus NS5 domain | Descriptor: | Genome polyprotein, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Talapatra, S.K, Chatrin, C, Kozielski, F. | Deposit date: | 2017-03-29 | Release date: | 2018-01-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping. Oncotarget, 9, 2018
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7V2Z
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![BU of 7v2z by Molmil](/molmil-images/mine/7v2z) | ZIKV NS3helicase in complex with ssRNA and ATP-Mn2+ | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Core protein, MANGANESE (II) ION, ... | Authors: | Lin, M.M, Yang, H.T. | Deposit date: | 2021-08-10 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.10101676 Å) | Cite: | Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis. Acs Infect Dis., 8, 2022
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5IY3
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![BU of 5iy3 by Molmil](/molmil-images/mine/5iy3) | Zika Virus Non-structural Protein NS1 | Descriptor: | Genome polyprotein | Authors: | Song, H, Qi, J, Shi, Y, Gao, G.F. | Deposit date: | 2016-03-23 | Release date: | 2016-04-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses Nat.Struct.Mol.Biol., 23, 2016
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