7M1V

Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation

Summary for 7M1V

• Entry DOI: 10.2210/pdb7m1v/pdb
• Related: 6um3
• Descriptor: Core protein, 4-(2-{2,4-diamino-5-[2-(4-{[(2E)-1,3-thiazolidin-2-ylidene]sulfamoyl}phenyl)hydrazinyl]phenyl}hydrazinyl)-N-[(2S)-1,3-thiazolidin-2-yl]benzene-1-sulfonamide, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: flavivirus, serine protease, zika virus, viral protein
• Biological source: Zika virus (ZIKV); More
• Total number of polymer chains: 2
• Total formula weight: 47205.93

Authors

Aleshin, A.E.,Shiryaev, S.A.,Liddington, R.C. (deposition date: 2021-03-15, release date: 2021-04-21, Last modification date: 2023-10-18)

• Primary citation: Aleshin, A.E.,Shiryaev, S.A.,Liddington, R.C.; To be provided; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)