7M1V

Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005524	molecular_function	ATP binding
A	0044423	cellular_component	virion component
B	0003723	molecular_function	RNA binding
B	0003724	molecular_function	RNA helicase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005524	molecular_function	ATP binding
B	0044423	cellular_component	virion component

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Charge relay system; for serine protease NS3 activity => ECO:0000255|PROSITE-ProRule:PRU00860

Chain	Residue	Details
A	HIS1051
A	ASP1075
A	SER1135
B	HIS1051
B	ASP1075
B	SER1135

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