5MRK

Structural basis of Zika virus methyltransferase inhibition by sinefungin

Summary for 5MRK

Entry DOI	10.2210/pdb5mrk/pdb
Descriptor	methyltransferase, SINEFUNGIN, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	zika, virus, methyltransferase, sinefungin, transferase
Biological source	Zika virus (strain Mr 766) (ZIKV)
Cellular location	Virion membrane ; Multi-pass membrane protein : A0A1B0YUR2
Total number of polymer chains	2
Total formula weight	59456.64
Authors	Hercik, K.,Boura, E. (deposition date: 2016-12-23, release date: 2017-01-25, Last modification date: 2024-01-17)
Primary citation	Hercik, K.,Brynda, J.,Nencka, R.,Boura, E. Structural basis of Zika virus methyltransferase inhibition by sinefungin. Arch. Virol., 162:2091-2096, 2017 Cited by PubMed: 28357511 DOI: 10.1007/s00705-017-3345-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation