5MRK
Structural basis of Zika virus methyltransferase inhibition by sinefungin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | methyltransferase | polymer | 265 | 29311.5 | 2 | UniProt (A0A1B0YUR2) Pfam (PF01728) UniProt (by SIFTS) (A0A024B7W1) | Zika virus (strain Mr 766) (ZIKV) | |
| 2 | C, E (A, B) | SINEFUNGIN | non-polymer | 381.4 | 2 | Chemie (SFG) | |||
| 3 | D, F (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: A0A1B0YUR2)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58623.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 833.7 | |
| All* | Total formula weight | 59456.6 |
