PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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4P9H	Crystal structure of 8ANC195 Fab in complex with gp120 of 93TH057 HIV-1 and soluble CD4 D1D2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Scharf, L, Bjorkman, P.J. 登録日 2014-04-04 公開日 2014-05-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike. Cell Rep, 7, 2014
8DTK	Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ... 著者 May, A.J, Manne, K, Acharya, P. 登録日 2022-07-25 公開日 2023-08-02 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.77 Å) 主引用文献 Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates. Biorxiv, 2023
7U0C	Crystal structure of broadly neutralizing antibody HEPC3.4 分子名称: HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2022-02-17 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nat Commun, 13, 2022
7U0B	Crystal structure of broadly neutralizing antibody HEPC3.1 分子名称: HEPC3.1 Fab Heavy Chain, HEPC3.1 Fab Light Chain 著者 Flyak, A.I, Bjorkman, P.J. 登録日 2022-02-17 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nat Commun, 13, 2022
4P9M	Crystal structure of 8ANC195 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, 8ANC195 light chain 著者 Scharf, L, Bjorkman, P.J. 登録日 2014-04-04 公開日 2014-05-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike. Cell Rep, 7, 2014
7LF2	Trimeric human Arginase 1 in complex with mAb4 分子名称: Arginase-1, MANGANESE (II) ION, mAb4 monoclonal antibody heavy chain, ... 著者 Gomez-Llorente, Y, Scapin, G, Palte, R.L. 登録日 2021-01-15 公開日 2021-09-01 実験手法 ELECTRON MICROSCOPY (3.72 Å) 主引用文献 Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action. Commun Biol, 4, 2021
7YHK	Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 分子名称: 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. 登録日 2022-07-13 公開日 2022-08-17 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
4HQQ	Crystal structure of RV144-elicited antibody CH58 分子名称: CH58 Fab heavy chain, CH58 Fab light chain 著者 McLellan, J.S, Haynes, B.F, Kwong, P.D. 登録日 2012-10-25 公開日 2013-02-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38, 2013
4HPY	Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide 分子名称: CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ... 著者 McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. 登録日 2012-10-24 公開日 2013-02-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38, 2013
4HPO	Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide 分子名称: CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ... 著者 McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. 登録日 2012-10-24 公開日 2013-02-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38, 2013
7T7B	Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ... 著者 Liu, H, Wilson, I.A. 登録日 2021-12-14 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron. Commun Biol, 5, 2022
7LCV	Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein 分子名称: CHLORIDE ION, Factor H binding protein, Immunoglobulin heavy chain Fd fragment, ... 著者 Beernink, P.T, Sands, N. 登録日 2021-01-11 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site. Plos Pathog., 17, 2021
4K94	Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibody Fab19 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab19 heavy chain, Fab19 light chain, ... 著者 Resheynyak, A.V, Boggon, T.J, Lax, I, Schlessinger, J. 登録日 2013-04-19 公開日 2013-10-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region. Proc.Natl.Acad.Sci.USA, 110, 2013
7UNB	Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-117 and RUPA-47 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-117 Fab heavy chain, ... 著者 Hailemariam, S, McLeod, B, Julien, J.-P. 登録日 2022-04-10 公開日 2022-08-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses. Immunity, 55, 2022
7TZG	Structure of human LAG3 in complex with antibody single-chain variable fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, scFvF7 著者 Ming, Q, Tran, T.H, Luca, V.C. 登録日 2022-02-15 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.71 Å) 主引用文献 LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition. Nat.Immunol., 23, 2022
4LKX	Humanized antibody 4B12 Fab complexed with a CemX segment 分子名称: CemX segment, Fab fragment heavy chain, Fab fragment light chain 著者 Chu, H.M, Wright, J, Chan, Y.H, Lin, C.J, Chang, T.W, Lim, C. 登録日 2013-07-09 公開日 2014-01-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations. Nat Commun, 5, 2014
7TZH	Structure of human LAG3 domains 3-4 in complex with antibody single chain-variable fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, scFvF7 著者 Ming, Q, Tran, T.H, Luca, V.C. 登録日 2022-02-15 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition. Nat.Immunol., 23, 2022
7VYT	Crystal structure of human TIGIT(23-129) in complex with the scFv fragment of anti-TIGIT antibody MG1131 分子名称: CITRATE ANION, MG1131 heavy chain variable region, MG1131 light chain variable region, ... 著者 Jeong, B.-S, Nam, H, Kim, M, Oh, B.-H. 登録日 2021-11-15 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structural and functional characterization of a monoclonal antibody blocking TIGIT. Mabs, 14, 2022
5HJ3	Crystal structure of host-primed Ebola virus GP, GPcl. 分子名称: Envelope glycoprotein, KZ52 Antibody Fragment, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Bornholdt, Z.A, Fusco, M.L, Saphire, E.O. 登録日 2016-01-12 公開日 2016-03-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies. Mbio, 7, 2016
7L06	Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ... 著者 Manne, K, Henderson, R, Acharya, P. 登録日 2020-12-11 公開日 2020-12-30 最終更新日 2021-06-09 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
7L2C	Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD) 分子名称: 2-51 heavy chain, 2-51 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cerutti, G, Reddem, E.R, Shapiro, L. 登録日 2020-12-16 公開日 2021-02-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29, 2021
7L02	Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ... 著者 Manne, K, Henderson, R, Acharya, P. 登録日 2020-12-10 公開日 2020-12-30 最終更新日 2021-06-09 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
7L09	Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound domain-swapped antibody 2G12 from masked 3D refinement 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ... 著者 Manne, K, Henderson, R, Acharya, P. 登録日 2020-12-11 公開日 2020-12-30 最終更新日 2021-06-09 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
6WTU	Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 273264 分子名称: 273264 Fab heavy chain, 273264 Fab light chain, reticulocyte binding protein 2b 著者 Chan, L.J, Dietrich, M.H, Tham, W.H. 登録日 2020-05-04 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b. Nat Commun, 12, 2021
6WQO	Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 283284 分子名称: 283284 Fab heavy chain, 283284 Fab light chain, reticulocyte binding protein 2b 著者 Chan, L.J, Dietrich, M.H, Tham, W.H. 登録日 2020-04-29 公開日 2021-01-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b. Nat Commun, 12, 2021

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