4LKX

Humanized antibody 4B12 Fab complexed with a CemX segment

Summary for 4LKX

• Entry DOI: 10.2210/pdb4lkx/pdb
• Descriptor: Fab fragment heavy chain, Fab fragment light chain, CemX segment, ... (4 entities in total)
• Functional Keywords: immunoglobulin, antibody, fab-peptide complex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 49094.73

Authors

Chu, H.M.,Wright, J.,Chan, Y.H.,Lin, C.J.,Chang, T.W.,Lim, C. (deposition date: 2013-07-09, release date: 2014-01-29, Last modification date: 2023-11-08)

• Primary citation: Chu, H.M.,Wright, J.,Chan, Y.H.,Lin, C.J.,Chang, T.W.,Lim, C.; Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.; Nat Commun, 5:3139-3139, 2014; PubMed: 24457896; DOI: 10.1038/ncomms4139

Experimental method

X-RAY DIFFRACTION (1.92 Å)