4HPO
Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
Summary for 4HPO
Entry DOI | 10.2210/pdb4hpo/pdb |
Related | 4HPY 4HQQ |
Descriptor | CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ... (5 entities in total) |
Functional Keywords | immunoglobulin, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 50906.62 |
Authors | McLellan, J.S.,Gorman, J.,Haynes, B.F.,Kwong, P.D. (deposition date: 2012-10-24, release date: 2013-02-06, Last modification date: 2023-09-20) |
Primary citation | Liao, H.X.,Bonsignori, M.,Alam, S.M.,McLellan, J.S.,Tomaras, G.D.,Moody, M.A.,Kozink, D.M.,Hwang, K.K.,Chen, X.,Tsao, C.Y.,Liu, P.,Lu, X.,Parks, R.J.,Montefiori, D.C.,Ferrari, G.,Pollara, J.,Rao, M.,Peachman, K.K.,Santra, S.,Letvin, N.L.,Karasavvas, N.,Yang, Z.Y.,Dai, K.,Pancera, M.,Gorman, J.,Wiehe, K.,Nicely, N.I.,Rerks-Ngarm, S.,Nitayaphan, S.,Kaewkungwal, J.,Pitisuttithum, P.,Tartaglia, J.,Sinangil, F.,Kim, J.H.,Michael, N.L.,Kepler, T.B.,Kwong, P.D.,Mascola, J.R.,Nabel, G.J.,Pinter, A.,Zolla-Pazner, S.,Haynes, B.F. Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38:176-186, 2013 Cited by PubMed: 23313589DOI: 10.1016/j.immuni.2012.11.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.694 Å) |
Structure validation
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