PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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3UZS	Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex 分子名称: Beta-adrenergic receptor kinase 1, C13.28 RNA Aptamer, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Tesmer, J.J.G, Tesmer, V.M. 登録日 2011-12-07 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.52 Å) 主引用文献 Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20, 2012
7BX0	Crystal structure of RTT109 from Candida albicans 分子名称: Histone acetyltransferase RTT109 著者 Lei, J.H, Chen, Y.P, Lu, D.R, Su, D. 登録日 2020-04-16 公開日 2021-04-21 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of RTT109 from Candida albicans To Be Published
3PYK	Human Carbonic Anhydrase II as Host for Pianostool Complexes Bearing a Sulfonamide Anchor 分子名称: Carbonic anhydrase 2, METHYL MERCURY ION, SULFATE ION, ... 著者 Heinisch, T, Schirmer, T. 登録日 2010-12-13 公開日 2011-07-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Human Carbonic Anhydrase II as a host for piano-stool complexes bearing a sulfonamide anchor. Chem.Commun.(Camb.), 47, 2011
2CLB	The structure of the DPS-like protein from Sulfolobus solfataricus reveals a bacterioferritin-like di-metal binding site within a Dps- like dodecameric assembly 分子名称: DPS-LIKE PROTEIN, FE (III) ION, ZINC ION 著者 Gauss, G.H, Benas, P, Wiedenheft, B, Young, M, Douglas, T, Lawrence, C.M. 登録日 2006-04-26 公開日 2006-07-17 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the Dps-Like Protein from Sulfolobus Solfataricus Reveals a Bacterioferritin-Like Dimetal Binding Site within a Dps-Like Dodecameric Assembly. Biochemistry, 45, 2006
6V2W	Crystal structure of the BRAF:MEK1 kinases in complex with AMPPNP 分子名称: Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Li, K, Gonzalez Del-Pino, G, Park, E, Eck, M.J. 登録日 2019-11-25 公開日 2020-12-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation. Proc.Natl.Acad.Sci.USA, 118, 2021
4BHW	Structural basis for autoinhibition of the acetyltransferase activity of p300 分子名称: HISTONE ACETYLTRANSFERASE P300, ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate 著者 Delvecchio, M, Gaucher, J, Aguilar-Gurrieri, C, Ortega, E, Panne, D. 登録日 2013-04-08 公開日 2013-08-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.799 Å) 主引用文献 Structure of the P300 Catalytic Core and Implications for Chromatin Targeting and Hat Regulation Nat.Struct.Mol.Biol., 20, 2013
1POD	STRUCTURES OF FREE AND INHIBITED HUMAN SECRETORY PHOSPHOLIPASE A2 FROM INFLAMMATORY EXUDATE 分子名称: CALCIUM ION, PHOSPHOLIPASE A2 著者 Scott, D.L, White, S.P, Sigler, P.B. 登録日 1992-09-07 公開日 1993-10-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of free and inhibited human secretory phospholipase A2 from inflammatory exudate. Science, 254, 1991
4HAI	Crystal structure of human soluble epoxide hydrolase complexed with N-cycloheptyl-1-(mesitylsulfonyl)piperidine-4-carboxamide. 分子名称: Bifunctional epoxide hydrolase 2, MAGNESIUM ION, N-cycloheptyl-1-[(2,4,6-trimethylphenyl)sulfonyl]piperidine-4-carboxamide, ... 著者 Pecic, S, Pakhomova, S, Newcomer, M.E, Morisseau, C, Hammock, B.D, Zhu, Z, Deng, S. 登録日 2012-09-26 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
1GOG	NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE 分子名称: COPPER (II) ION, GALACTOSE OXIDASE, SODIUM ION 著者 Ito, N, Phillips, S.E.V, Knowles, P.F. 登録日 1993-09-30 公開日 1994-01-31 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Nature, 350, 1991
6SBM	Human Carbonic Anhydrase II in complex with 4-(pentyloxy)benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-pentoxybenzenesulfonamide, CITRATE ANION, ... 著者 Gloeckner, S, Ngo, K, Heine, A, Klebe, G. 登録日 2019-07-21 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Human Carbonic Anhydrase II in complex with 4-(pentyloxy)benzenesulfonamide To Be Published
4DK8	Crystal structure of LXR ligand binding domain in complex with partial agonist 5 分子名称: ACETATE ION, CALCIUM ION, N-methyl-N-(4-{(1S)-2,2,2-trifluoro-1-hydroxy-1-[1-(2-methoxyethyl)-1H-pyrrol-2-yl]ethyl}phenyl)benzenesulfonamide, ... 著者 Piper, D.E, Kopecky, D.J, Xu, H. 登録日 2012-02-03 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Discovery of a new binding mode for a series of liver X receptor agonists. Bioorg.Med.Chem.Lett., 22, 2012
1A97	XPRTASE FROM E. COLI COMPLEXED WITH GMP 分子名称: BORIC ACID, GUANOSINE-5'-MONOPHOSPHATE, XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE 著者 Vos, S, Parry, R.J, Burns, M.R, De Jersey, J, Martin, J.L. 登録日 1998-04-16 公開日 1998-11-11 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase. J.Mol.Biol., 282, 1998
6I7N	Trypanothione Reductase from Leismania infantum in complex with TRL156 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... 著者 Carriles, A.A, Hermoso, J.A. 登録日 2018-11-16 公開日 2019-05-15 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase. Acs Infect Dis., 5, 2019
1Q24	PKA double mutant model of PKB in complex with MgATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent Protein Kinase Inhibitor, ... 著者 Gassel, M, Breitenlechner, C.B, Rueger, P, Jucknischke, U, Schneider, T, Huber, R, Bossemeyer, D, Engh, R.A. 登録日 2003-07-23 公開日 2003-08-19 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Mutants of protein kinase A that mimic the ATP-binding site of protein kinase B (AKT) J.Mol.Biol., 329, 2003
6SFU	Human Carbonic Anhydrase II in complex with a furan-containing benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-(furan-2-ylmethylamino)benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-08-02 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Human Carbonic Anhydrase II in complex with a furan-containing benzenesulfonamide To Be Published
5A7Z	Crystal structure of Sulfolobus acidocaldarius Trm10 at 2.1 angstrom resolution. 分子名称: TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE 著者 Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W. 登録日 2015-07-10 公開日 2016-01-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue. Nucleic Acids Res., 44, 2016
4BLO	P4 PROTEIN FROM BACTERIOPHAGE PHI6 IN COMPLEX WITH ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PACKAGING ENZYME P4 著者 El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. 登録日 2013-05-04 公開日 2013-08-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
6V8F	Crystal structure of recombinat mutant Q185R of human fumarase 分子名称: CHLORIDE ION, Fumarate hydratase, mitochondrial, ... 著者 Ajalla, M.A.A, Nonato, M.C. 登録日 2019-12-11 公開日 2020-12-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of recombinat mutant Q185R of human fumarase To Be Published
1AHL	ANTHOPLEURIN-A,NMR, 20 STRUCTURES 分子名称: ANTHOPLEURIN-A 著者 Pallaghy, P.K, Scanlon, M.J, Monks, S.A, Norton, R.S. 登録日 1994-10-28 公開日 1995-11-14 最終更新日 2024-11-20 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structure in solution of the polypeptide cardiac stimulant anthopleurin-A. Biochemistry, 34, 1995
4DCK	Crystal structure of the C-terminus of voltage-gated sodium channel in complex with FGF13 and CaM 分子名称: Calmodulin, Fibroblast growth factor 13, MAGNESIUM ION, ... 著者 Chung, B.C, Wang, C, Yan, H, Pitt, G.S, Lee, S.Y. 登録日 2012-01-17 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and Calmodulin. Structure, 20, 2012
2FJU	Activated Rac1 bound to its effector phospholipase C beta 2 分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CALCIUM ION, ... 著者 Jezyk, M.R, Snyder, J.T, Harden, T.K, Sondek, J. 登録日 2006-01-03 公開日 2006-11-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Rac1 bound to its effector phospholipase C-beta2. Nat.Struct.Mol.Biol., 13, 2006
7BG9	The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate 分子名称: DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ... 著者 Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. 登録日 2021-01-06 公開日 2021-04-28 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
4HG3	Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with alpha-ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, CACODYLATE ION, GLYCEROL, ... 著者 Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. 登録日 2012-10-06 公開日 2013-07-31 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69, 2013
6SDI	Human Carbonic Anhydrase II in complex with an inhibitor soaked at a concentration of 0.01 mM 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Gloeckner, S, Haake, M, Heine, A, Klebe, G. 登録日 2019-07-27 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Human Carbonic Anhydrase II in complex with an inhibitor soaked at a concentration of 0.01 mM To Be Published
6V9X	Structure of TRPA1 modified by iodoacetamide, PMAL-C8 分子名称: Transient receptor potential cation channel subfamily A member 1 著者 Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. 登録日 2019-12-16 公開日 2020-05-06 最終更新日 2025-04-02 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature, 585, 2020

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