2FJU

Activated Rac1 bound to its effector phospholipase C beta 2

Summary for 2FJU

Entry DOI	10.2210/pdb2fju/pdb
Descriptor	Ras-related C3 botulinum toxin substrate 1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	protein-protein complex, signaling protein, apoptosis-hydrolase complex, apoptosis/hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P63000
Total number of polymer chains	2
Total formula weight	111435.39
Authors	Jezyk, M.R.,Snyder, J.T.,Harden, T.K.,Sondek, J. (deposition date: 2006-01-03, release date: 2006-11-21, Last modification date: 2024-02-14)
Primary citation	Jezyk, M.R.,Snyder, J.T.,Gershberg, S.,Worthylake, D.K.,Harden, T.K.,Sondek, J. Crystal structure of Rac1 bound to its effector phospholipase C-beta2. Nat.Struct.Mol.Biol., 13:1135-1140, 2006 Cited by PubMed: 17115053 DOI: 10.1038/nsmb1175 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation