2FJU

Activated Rac1 bound to its effector phospholipase C beta 2

Summary for 2FJU

DescriptorRas-related C3 botulinum toxin substrate 1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsprotein-protein complex, signaling protein, apoptosis-hydrolase complex, apoptosis/hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (By similarity) P63000
Total number of polymer chains2
Total molecular weight111435.39
Authors
Jezyk, M.R.,Snyder, J.T.,Harden, T.K.,Sondek, J. (deposition date: 2006-01-03, release date: 2006-11-21, Last modification date: 2011-07-13)
Primary citation
Jezyk, M.R.,Snyder, J.T.,Gershberg, S.,Worthylake, D.K.,Harden, T.K.,Sondek, J.
Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13:1135-1140, 2006
PubMed: 17115053 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1175
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.226130.2%2.9%4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution