2FJU
Activated Rac1 bound to its effector phospholipase C beta 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras-related C3 botulinum toxin substrate 1 | polymer | 178 | 19797.8 | 1 | UniProt (P63000) Pfam (PF00071) | Homo sapiens (human) | p21-Rac1; Ras-like protein TC25 |
| 2 | B (B) | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 | polymer | 799 | 91033.9 | 1 | UniProt (Q00722) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) | Homo sapiens (human) | Phosphoinositide phospholipase C; Phospholipase C- beta-2; PLC-beta-2 |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 5 | E (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 486 | Chemie (HOH) |
Sequence modifications
A: 1 - 177 (UniProt: P63000)
| PDB | External Database | Details |
|---|---|---|
| Ser 178 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110831.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 603.6 | |
| All* | Total formula weight | 111435.4 |
