1Q24

PKA double mutant model of PKB in complex with MgATP

Summary for 1Q24

• Entry DOI: 10.2210/pdb1q24/pdb
• Related: 1CDK 1Q61 1Q62
• Descriptor: cAMP-dependent Protein Kinase, alpha-catalytic subunit, cAMP-dependent Protein Kinase Inhibitor, alpha form, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: q181 switch, mg-atp binding, pkb-model, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Bos taurus (cattle); More
• Cellular location: Cytoplasm: P00517
• Total number of polymer chains: 2
• Total formula weight: 43454.29

Authors

Gassel, M.,Breitenlechner, C.B.,Rueger, P.,Jucknischke, U.,Schneider, T.,Huber, R.,Bossemeyer, D.,Engh, R.A. (deposition date: 2003-07-23, release date: 2003-08-19, Last modification date: 2021-10-27)

• Primary citation: Gassel, M.,Breitenlechner, C.B.,Rueger, P.,Jucknischke, U.,Schneider, T.,Huber, R.,Bossemeyer, D.,Engh, R.A.; Mutants of protein kinase A that mimic the ATP-binding site of protein kinase B (AKT); J.Mol.Biol., 329:1021-1034, 2003; PubMed: 12798691; DOI: 10.1016/S0022-2836(03)00518-7

Experimental method

X-RAY DIFFRACTION (2.6 Å)