7BG9

The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate

Summary for 7BG9

• Entry DOI: 10.2210/pdb7bg9/pdb
• Related: 7BGB
• EMDB information: 12174 12175 12176 12177
• Descriptor: Telomerase reverse transcriptase,Telomerase reverse transcriptase, DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2B, ... (5 entities in total)
• Functional Keywords: reverse transcriptase, ribonucleoprotein, complex, dna, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 332366.46

Authors

Nguyen, T.H.D.,Ghanim, G.E.,Fountain, A.J.,van Roon, A.M.M.,Rangan, R.,Das, R.,Collins, K. (deposition date: 2021-01-06, release date: 2021-04-28, Last modification date: 2021-06-02)

• Primary citation: Ghanim, G.E.,Fountain, A.J.,van Roon, A.M.,Rangan, R.,Das, R.,Collins, K.,Nguyen, T.H.D.; Structure of human telomerase holoenzyme with bound telomeric DNA.; Nature, 593:449-453, 2021; PubMed: 33883742; DOI: 10.1038/s41586-021-03415-4

Experimental method

ELECTRON MICROSCOPY (3.8 Å)