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7BG9

The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATelomerase reverse transcriptase,Telomerase reverse transcriptasepolymer1332149158.61UniProt (O14746)
Pfam (PF12009)
Pfam (PF00078)
Pfam (PF21399)
In PDB
Homo sapiens (Human)HEST2,Telomerase catalytic subunit,Telomerase-associated protein 2,TP2
2NDNA (5'-D(P*TP*TP*AP*GP*GP*G)-3')polymer185514.61synthetic construct
3MHistone H2Bpolymer16618074.91UniProt (B4DR52)
Pfam (PF00125)
In PDB
Homo sapiens (Human)
4LHistone H2Apolymer13014140.61UniProt (B2R5B3)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P0C0S8)
In PDB
Homo sapiens (Human)
5BRNA (256-MER)polymer451145477.81Homo sapiens (Human)
Sequence modifications
A: -199 - 0 (PDB: 7BG9)
A: 1 - 1132 (UniProt: O14746)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight332366.5
All*Total formula weight332366.5
*Water molecules are not included.

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PDB entries from 2024-07-17

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