2Z2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z2s by Molmil](/molmil-images/mine/2z2s) | |
7KTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ktp by Molmil](/molmil-images/mine/7ktp) | PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | 著者 | Grau, D.J, Armache, K.J. | 登録日 | 2020-11-24 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
|
|
7YHJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yhj by Molmil](/molmil-images/mine/7yhj) | |
3DEU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3deu by Molmil](/molmil-images/mine/3deu) | Crystal structure of transcription regulatory protein slyA from Salmonella typhimurium in complex with salicylate ligands | 分子名称: | 2-HYDROXYBENZOIC ACID, Transcriptional regulator slyA | 著者 | Le Trong, I, Brzovic, P.S, Fang, F.C, Libby, S.J, Stenkamp, R.E. | 登録日 | 2008-06-10 | 公開日 | 2008-06-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Evolution of SlyA/RovA Transcription Factors from Repressors to Countersilencers in Enterobacteriaceae . Mbio, 10, 2019
|
|
5FA5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fa5 by Molmil](/molmil-images/mine/5fa5) | |
3BT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bt9 by Molmil](/molmil-images/mine/3bt9) | |
3BTI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bti by Molmil](/molmil-images/mine/3bti) | |
2FJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fj1 by Molmil](/molmil-images/mine/2fj1) | Crystal Structure Analysis of Tet Repressor (class D) in Complex with 7-Chlortetracycline-Nickel(II) | 分子名称: | 7-CHLOROTETRACYCLINE, CHLORIDE ION, NICKEL (II) ION, ... | 著者 | Orth, P, Saenger, W, Palm, G.J, Hinrichs, W. | 登録日 | 2005-12-30 | 公開日 | 2007-01-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Specific binding of divalent metal ions to tetracycline and to the Tet repressor/tetracycline complex. J.Biol.Inorg.Chem., 13, 2008
|
|
7NSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nsq by Molmil](/molmil-images/mine/7nsq) | |
7NSO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nso by Molmil](/molmil-images/mine/7nso) | |
7NSP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nsp by Molmil](/molmil-images/mine/7nsp) | |
7KSO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kso by Molmil](/molmil-images/mine/7kso) | Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2 | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | 著者 | Grau, D.J, Armache, K.J. | 登録日 | 2020-11-23 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
|
|
7KSR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ksr by Molmil](/molmil-images/mine/7ksr) | PRC2:EZH1_A from a dimeric PRC2 bound to a nucleosome | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | 著者 | Grau, D.J, Armache, K.J. | 登録日 | 2020-11-24 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
|
|
3BR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3br3 by Molmil](/molmil-images/mine/3br3) | |
4L5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l5i by Molmil](/molmil-images/mine/4l5i) | |
4L5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l5j by Molmil](/molmil-images/mine/4l5j) | |
6YUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yuh by Molmil](/molmil-images/mine/6yuh) | Crystal structure of SMYD3 with diperodon R enantiomer bound to allosteric site | 分子名称: | Diperodon, GLYCEROL, Histone-lysine N-methyltransferase SMYD3, ... | 著者 | Cederfelt, D, Talibov, V.O, Dobritzsch, D, Danielson, U.H. | 登録日 | 2020-04-27 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase. Chembiochem, 22, 2021
|
|
3TPE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tpe by Molmil](/molmil-images/mine/3tpe) | The phipa p3121 structure | 分子名称: | Serine/threonine-protein kinase HipA | 著者 | Schumacher, M.A, Link, T, Brennan, R.G. | 登録日 | 2011-09-07 | 公開日 | 2012-10-03 | 最終更新日 | 2018-03-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
|
|
6ZHC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zhc by Molmil](/molmil-images/mine/6zhc) | PROTAC6 mediated complex of VHL:EloB:EloC and Bcl-xL | 分子名称: | 1,2-ETHANEDIOL, 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]-5-[3-[4-[3-[2-[2-[2-[2-[2-[3-[[(2~{S})-3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-ynyl]phenoxy]propyl]-1,3-thiazole-4-carboxylic acid, Bcl-2-like protein 1, ... | 著者 | Chung, C. | 登録日 | 2020-06-22 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. Acs Chem.Biol., 15, 2020
|
|
6YZ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yz3 by Molmil](/molmil-images/mine/6yz3) | PqsR (MvfR) in complex with antagonist 19 | 分子名称: | 1,2-ETHANEDIOL, 6-chloranyl-3-[(2-hexyl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one, LysR family transcriptional regulator | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2020-05-06 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
|
|
6U48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u48 by Molmil](/molmil-images/mine/6u48) | E. coli 50S with phazolicin (PHZ) bound in exit tunnel | 分子名称: | 23S rRNA, 50S ribosomal protein bL17, 50S ribosomal protein bL19, ... | 著者 | Watson, Z.L, Cate, J.H.D, Polikanov, Y.S, Severinov, K. | 登録日 | 2019-08-23 | 公開日 | 2019-09-18 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition. Nat Commun, 10, 2019
|
|
6Z07
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z07 by Molmil](/molmil-images/mine/6z07) | PqsR (MvfR) in complex with antagonist 12 | 分子名称: | 3-[(2-~{tert}-butyl-1,3-thiazol-4-yl)methyl]-6-chloranyl-quinazolin-4-one, GLYCEROL, Transcriptional regulator MvfR | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2020-05-07 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
|
|
6Z5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z5k by Molmil](/molmil-images/mine/6z5k) | PqsR (MvfR) in complex with antagonist 18 | 分子名称: | 6-chloranyl-3-[(2-pentyl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one, Transcriptional regulator MvfR | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2020-05-26 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | 主引用文献 | Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur.J.Med.Chem., 208, 2020
|
|
3TPB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tpb by Molmil](/molmil-images/mine/3tpb) | Structure of HipA(S150A) | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Serine/threonine-protein kinase HipA | 著者 | schumacher, M.A. | 登録日 | 2011-09-07 | 公開日 | 2012-10-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance. Cell Rep, 2, 2012
|
|
6Z7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z7o by Molmil](/molmil-images/mine/6z7o) | Crystal structure of Thioredoxin T from Drosophila melanogaster | 分子名称: | Thioredoxin-T, ZINC ION | 著者 | Freier, R, Aragon, E, Baginski, B, Pluta, R, Martin-Malpartida, P, Torner, C, Gonzaez, C, Macias, M. | 登録日 | 2020-05-31 | 公開日 | 2020-10-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins. Iucrj, 8, 2021
|
|