7KSO
Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2
Summary for 7KSO
Entry DOI | 10.2210/pdb7kso/pdb |
EMDB information | 23021 |
Descriptor | Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ... (7 entities in total) |
Functional Keywords | chromatin, methyltransferase, nucleosome-modifying complex, gene regulation, gene regulation-transferase complex, gene regulation/transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 439068.94 |
Authors | Grau, D.J.,Armache, K.J. (deposition date: 2020-11-23, release date: 2021-02-03, Last modification date: 2024-03-06) |
Primary citation | Grau, D.,Zhang, Y.,Lee, C.H.,Valencia-Sanchez, M.,Zhang, J.,Wang, M.,Holder, M.,Svetlov, V.,Tan, D.,Nudler, E.,Reinberg, D.,Walz, T.,Armache, K.J. Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12:714-714, 2021 Cited by PubMed: 33514705DOI: 10.1038/s41467-020-20775-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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