7KSO

Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2

Summary for 7KSO

Entry DOI	10.2210/pdb7kso/pdb
EMDB information	23021
Descriptor	Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ... (7 entities in total)
Functional Keywords	chromatin, methyltransferase, nucleosome-modifying complex, gene regulation, gene regulation-transferase complex, gene regulation/transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	439068.94
Authors	Grau, D.J.,Armache, K.J. (deposition date: 2020-11-23, release date: 2021-02-03, Last modification date: 2024-03-06)
Primary citation	Grau, D.,Zhang, Y.,Lee, C.H.,Valencia-Sanchez, M.,Zhang, J.,Wang, M.,Holder, M.,Svetlov, V.,Tan, D.,Nudler, E.,Reinberg, D.,Walz, T.,Armache, K.J. Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12:714-714, 2021 Cited by PubMed: 33514705 DOI: 10.1038/s41467-020-20775-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation