6Z5K

PqsR (MvfR) in complex with antagonist 18

This is a non-PDB format compatible entry.

Summary for 6Z5K

• Entry DOI: 10.2210/pdb6z5k/pdb
• Related: 6YZ3
• Descriptor: Transcriptional regulator MvfR, 6-chloranyl-3-[(2-pentyl-2,3-dihydro-1,3-thiazol-4-yl)methyl]quinazolin-4-one (3 entities in total)
• Functional Keywords: pseudomonas aeruginosa, antagonist, quorum sensing, dna binding protein
• Biological source: Pseudomonas aeruginosa (strain UCBPP-PA14)
• Total number of polymer chains: 1
• Total formula weight: 27097.06

Authors

Richardson, W.K.,Emsley, J. (deposition date: 2020-05-26, release date: 2020-09-16, Last modification date: 2024-01-24)

• Primary citation: Grossman, S.,Soukarieh, F.,Richardson, W.,Liu, R.,Mashabi, A.,Emsley, J.,Williams, P.,Camara, M.,Stocks, M.J.; Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR.; Eur.J.Med.Chem., 208:112778-112778, 2020; PubMed: 32927392; DOI: 10.1016/j.ejmech.2020.112778

Experimental method

X-RAY DIFFRACTION (3.201 Å)