7NSO

Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with P-tRNA

This is a non-PDB format compatible entry.

Summary for 7NSO

• Entry DOI: 10.2210/pdb7nso/pdb
• EMDB information: 12573
• Descriptor: 23S rRNA (2903-MER), 50S ribosomal protein L14, 50S ribosomal protein L15, ... (56 entities in total)
• Functional Keywords: antibiotic, ermdl, erythromycin, macrolide, stalling, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 55
• Total formula weight: 2143698.54

Authors

Beckert, B.,Wilson, D.N. (deposition date: 2021-03-08, release date: 2021-07-14, Last modification date: 2021-08-11)

• Primary citation: Beckert, B.,Leroy, E.C.,Sothiselvam, S.,Bock, L.V.,Svetlov, M.S.,Graf, M.,Arenz, S.,Abdelshahid, M.,Seip, B.,Grubmuller, H.,Mankin, A.S.,Innis, C.A.,Vazquez-Laslop, N.,Wilson, D.N.; Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.; Nat Commun, 12:4466-4466, 2021; PubMed: 34294725; DOI: 10.1038/s41467-021-24674-9

Experimental method

ELECTRON MICROSCOPY (2.9 Å)