7KTP

PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome

Summary for 7KTP

• Entry DOI: 10.2210/pdb7ktp/pdb
• Related: 7KSO 7KSR
• EMDB information: 23021 23022 23024 23025
• Descriptor: Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ... (5 entities in total)
• Functional Keywords: chromatin, methyltransferase, nucleosome-modifying complex, gene regulation, gene regulation-transferase complex, gene regulation/transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 267011.14

Authors

Grau, D.J.,Armache, K.J. (deposition date: 2020-11-24, release date: 2021-02-03, Last modification date: 2024-03-06)

• Primary citation: Grau, D.,Zhang, Y.,Lee, C.H.,Valencia-Sanchez, M.,Zhang, J.,Wang, M.,Holder, M.,Svetlov, V.,Tan, D.,Nudler, E.,Reinberg, D.,Walz, T.,Armache, K.J.; Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.; Nat Commun, 12:714-714, 2021; PubMed: 33514705; DOI: 10.1038/s41467-020-20775-z

Experimental method

ELECTRON MICROSCOPY (4.8 Å)