PDB: 541 件ウェブページステータス検索Chemie searchBIRD

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3IGK	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 2) 分子名称: Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ZINC ION 著者 Suad, O, Rabinovich, D, Rozenberg, H, Shakked, Z. 登録日 2009-07-28 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
3IGL	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 1) 分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ... 著者 Kitayner, M, Suad, O, Rozenberg, H, Shakked, Z. 登録日 2009-07-28 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
3KZ8	Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3) 分子名称: Cellular tumor antigen p53, DNA (5'-D(*TP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*C)-3'), IODIDE ION, ... 著者 Rozenberg, H, Suad, O, Shakked, Z. 登録日 2009-12-08 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs Nat.Struct.Mol.Biol., 17, 2010
4CZ6	Truncated tetramerization domain of zebrafish p53 (crystal form II) 分子名称: CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER 著者 Joerger, A.C. 登録日 2014-04-16 公開日 2014-08-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Tracing the Evolution of the P53 Tetramerization Domain Structure, 22, 2014
3FEA	Crystal Structure of HdmX bound to the p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2 at 1.33A 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Mdm4 protein, p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2 著者 Kallen, J. 登録日 2008-11-28 公開日 2009-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes J.Biol.Chem., 284, 2009
3FE7	Crystal Structure of HdmX bound to the p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-Trp-Glu-Ac3c-Leu-NH2 at 1.35A 分子名称: Mdm4 protein, p53-peptidomimetic Ac-Phe-Met-Aib-Pmp-Trp-Glu-Ac3c-Leu-NH2 著者 Kallen, J. 登録日 2008-11-28 公開日 2009-01-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes J.Biol.Chem., 284, 2009
2WGX	HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-Y236F-N239Y-T253I-N268D 分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Khoo, K.H, Fersht, A.R. 登録日 2009-04-27 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Stabilising the DNA-Binding Domain of P53 by Rational Design of its Hydrophobic Core. Protein Eng.Des.Sel., 22, 2009
8F2H	Wild type P53 dimer structure from human cancer cells 分子名称: Cellular tumor antigen p53 著者 Solares, M, Kelly, D.F. 登録日 2022-11-08 公開日 2022-11-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials. Chembiochem, 23, 2022
2X0W	STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 5,6-dimethoxy- 2-methylbenzothiazole 分子名称: 5,6-DIMETHOXY-2-METHYL-1,3-BENZOTHIAZOLE, CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Kaar, J.L, Basse, N, Joerger, A.C, Fersht, A.R. 登録日 2009-12-17 公開日 2010-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol., 17, 2010
2X0U	STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-amino substituted benzothiazole scaffold 分子名称: 6,7-DIHYDRO[1,4]DIOXINO[2,3-F][1,3]BENZOTHIAZOL-2-AMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Kaar, J.L, Basse, N, Fersht, A.R. 登録日 2009-12-17 公開日 2010-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol., 17, 2010
2X0V	STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 4-(trifluoromethyl)benzene-1,2-diamine 分子名称: 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Basse, N, Kaar, J.L, Joerger, A.C, Fersht, A.R. 登録日 2009-12-17 公開日 2010-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol., 17, 2010
3LH0	Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2 分子名称: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ... 著者 Roy, S, Kutateladze, T.G. 登録日 2010-01-21 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J.Mol.Biol., 398, 2010
3LGF	Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2 分子名称: DIMETHYLATED p53 Lysine 370 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ... 著者 Roy, S, Kutateladze, T.G. 登録日 2010-01-20 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J.Mol.Biol., 398, 2010
3LGL	Crystal structure of the 53BP1 tandem tudor domain in complex with p53K382me2 分子名称: DIMETHYLATED p53 LYSINE 382 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ... 著者 Roy, S, Kutateladze, T.G. 登録日 2010-01-20 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J.Mol.Biol., 398, 2010
3KMD	Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer 分子名称: 5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*TP*AP*GP*GP*CP*AP*TP*GP*CP*C)-3', Cellular tumor antigen p53, ZINC ION 著者 Chen, Y, Dey, R, Chen, L. 登録日 2009-11-10 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer. Structure, 18, 2010
1DT7	SOLUTION STRUCTURE OF THE C-TERMINAL NEGATIVE REGULATORY DOMAIN OF P53 IN A COMPLEX WITH CA2+-BOUND S100B(BB) 分子名称: CALCIUM ION, CELLULAR TUMOR ANTIGEN P53, S100 CALCIUM-BINDING PROTEIN 著者 Rustandi, R.R, Baldisseri, D.M, Weber, D.J. 登録日 2000-01-11 公開日 2000-07-26 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Structure of the negative regulatory domain of p53 bound to S100B(betabeta). Nat.Struct.Biol., 7, 2000
6K4N	Cryo-EM structure of p300 分子名称: Histone acetyltransferase p300 著者 Ghosh, R, Roy, S, Sengupta, J. 登録日 2019-05-24 公開日 2019-06-19 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (9.8 Å) 主引用文献 Tumor Suppressor p53-Mediated Structural Reorganization of the Transcriptional Coactivator p300. Biochemistry, 58, 2019
7RM4	Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2 分子名称: 6-11 T cell receptor alpha chain, 6-11 T cell receptor beta chain, Beta-2-microglobulin, ... 著者 Wu, D, Mariuzza, R.A. 登録日 2021-07-26 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.33 Å) 主引用文献 T cell receptors employ diverse strategies to target a p53 cancer neoantigen. J.Biol.Chem., 298, 2022
1MA3	Structure of a Sir2 enzyme bound to an acetylated p53 peptide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cellular tumor antigen p53, Transcriptional regulatory protein, ... 著者 Avalos, J.L, Celic, I, Muhammad, S, Cosgrove, M.S, Boeke, J.D, Wolberger, C. 登録日 2002-07-31 公開日 2002-10-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of a Sir2 enzyme bound to an acetylated p53 peptide Mol.Cell, 10, 2002
1JSP	NMR Structure of CBP Bromodomain in complex with p53 peptide 分子名称: CREB-BINDING PROTEIN, tumor protein p53 著者 He, Y, Mujtaba, S, Zeng, L, Yan, S, Zhou, M.-M. 登録日 2001-08-17 公開日 2002-08-17 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. Mol.Cell, 13, 2004
2UZ8	The crystal structure of p18, human translation elongation factor 1 epsilon 1 分子名称: EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, GLYCEROL 著者 Kang, B.S, Kim, K.J, Kim, M.H, Oh, Y.S, Kim, S. 登録日 2007-04-26 公開日 2008-03-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Determination of Three-Dimensional Structure and Residues of the Novel Tumor Suppressor Aimp3/P18 Required for the Interaction with Atm. J.Biol.Chem., 283, 2008
1FIT	FHIT (FRAGILE HISTIDINE TRIAD PROTEIN) 分子名称: FRAGILE HISTIDINE PROTEIN, SULFATE ION, beta-D-fructofuranose 著者 Lima, C.D, D'Amico, K.L, Naday, I, Rosenbaum, G, Westbrook, E.M, Hendrickson, W.A. 登録日 1997-05-17 公開日 1997-11-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family. Structure, 5, 1997
8XP5	The Crystal Structure of p53/BCL-xL fusion complex from Biortus. 分子名称: Bcl-2-like protein 1,Cellular tumor antigen p53, ZINC ION 著者 Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. 登録日 2024-01-03 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The Crystal Structure of p53/BCL-xL fusion complex from Biortus. To Be Published
8R1F	Monomeric E6AP-E6-p53 ternary complex 分子名称: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... 著者 Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. 登録日 2023-11-01 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Monomeric E6AP-E6-p53 ternary complex To Be Published
8R1G	Dimeric ternary structure of E6AP-E6-p53 分子名称: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... 著者 Sandate, C.R, Chakrabory, D, Kater, L, Kempf, G, Thoma, N.H. 登録日 2023-11-01 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Monomeric E6AP-E6-p53 ternary complex To Be Published

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