1JSP

NMR Structure of CBP Bromodomain in complex with p53 peptide

Summary for 1JSP
Descriptortumor protein p53, CREB-BINDING PROTEIN (2 entities in total)
Functional Keywordsbromodomain, cbp, nmr structure., dna binding protein
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
Cytoplasm: Q92793
Total number of polymer chains2
Total formula weight16825.44
Authors
He, Y.,Mujtaba, S.,Zeng, L.,Yan, S.,Zhou, M.-M. (deposition date: 2001-08-17, release date: 2002-08-17, Last modification date: 2011-07-13)
Primary citationHe, Y.,Mujtaba, S.,Plotnikova, O.,Ronai, Z.,Sachchidanand,Sanchez, R.,Yan, S.,Zeleznik-Le, N.J.,Zeng, L.,Zhou, M.M.
Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Mol.Cell, 13:251-263, 2004
PubMed: 14759370
DOI: 110.1016/S1097-2765(03)00528-8
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation
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PDB entries from 2021-06-16