PDB: 292 件ウェブページステータス検索Chemie searchBIRD

---

1JPP	The Structure of a beta-Catenin Binding Repeat from Adenomatous Polyposis Coli (APC) in Complex with beta-Catenin 分子名称: ADENOMATOUS POLYPOSIS COLI PROTEIN, BETA-CATENIN, GLYCEROL 著者 Spink, K.E, Fridman, S.G, Weis, W.I. 登録日 2001-08-02 公開日 2002-01-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. EMBO J., 20, 2001
1LUJ	Crystal Structure of the Beta-catenin/ICAT Complex 分子名称: Beta-catenin-interacting protein 1, Catenin beta-1 著者 Graham, T.A, Clements, W.K, Kimelman, D, Xu, W. 登録日 2002-05-22 公開日 2002-10-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. Mol.Cell, 10, 2002
1M1E	Beta-catenin armadillo repeat domain bound to ICAT 分子名称: Beta-catenin, ICAT 著者 Daniels, D.L, Weis, W.I. 登録日 2002-06-18 公開日 2002-10-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 ICAT inhibits Beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules. Mol.Cell, 10, 2002
7RG1	Importin alpha2 in complex with MERS ORF4B H26A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Importin alpha2 in complex with MERS ORF4B NLS H26A mutant To Be Published
7RFY	Importin alpha3 in complex with MERS ORF4B 分子名称: Importin subunit alpha-3, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG0	Importin alpha2 in complex with MERS ORF4B R24A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RFX	Importin alpha2 in complex with MERS ORF4B 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RFZ	Importin alpha 2 in complex with MERS ORF4B NLS peptide 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG2	Importin alpha2 in complex with MERS ORF4B R33A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-08-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG6	Importin alpha2 in complex with ORF4B Bat coronavirus HKU5 分子名称: Importin subunit alpha-1, Non-structural protein ORF4b 著者 Foster, J.K, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-08-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG3	Importin alpha2 in complex with MERS ORF4B R37A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-08-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG4	Importin alpha2 in complex with p50 NLS 分子名称: Importin subunit alpha-1, Isoform 3 of Nuclear factor NF-kappa-B p105 subunit 著者 Smith, K.M, Tsimbalyuk, S, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-08-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
7RG5	Importin alpha3 in complex with p50 NLS 分子名称: Importin subunit alpha-3, Isoform 3 of Nuclear factor NF-kappa-B p105 subunit 著者 Smith, K.M, Tsimbalyuk, S, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-08-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
4UAF	Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain 分子名称: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2 著者 Pumroy, R.A, Cingolani, G. 登録日 2014-08-08 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
4U2X	Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus 分子名称: CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24 著者 Xu, W, Leung, D, Borek, D, Amarasinghe, G. 登録日 2014-07-18 公開日 2014-08-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.153 Å) 主引用文献 Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host Microbe, 16, 2014
4U5L	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5V	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5N	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5S	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U54	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-24 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5U	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U58	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-24 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5O	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
3QHE	Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis coli and the tyrosine-rich domain of Sam68 分子名称: Adenomatous polyposis coli protein, KH domain-containing, RNA-binding, ... 著者 Morishita, E.C.J, Murayama, K, Kato-Murayama, M, Ishizuku-Katsura, Y, Tomabechi, Y, Terada, T, Handa, N, Shirouzu, M, Akiyama, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2011-01-25 公開日 2011-11-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68 Structure, 19, 2011
4UAD	Importin alpha 7 delta IBB in complex with Influenza PB2 Nuclear Localization Domain 分子名称: Importin subunit alpha-7, Polymerase basic protein 2 著者 Pumroy, R.A, Cingolani, G. 登録日 2014-08-08 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015

<23456789101112>