7RG0
Importin alpha2 in complex with MERS ORF4B R24A mutant
Summary for 7RG0
Entry DOI | 10.2210/pdb7rg0/pdb |
Descriptor | Importin subunit alpha-1, ORF4b (3 entities in total) |
Functional Keywords | complex, transportin, importin, virus, transport protein, transport protein-viral protein complex, transport protein/viral protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 57893.67 |
Authors | Munasinghe, T.S.,Tsimbalyuk, S.,Roby, J.A.,Aragao, D.,Forwood, J.K. (deposition date: 2021-07-14, release date: 2021-07-28, Last modification date: 2023-10-25) |
Primary citation | Munasinghe, T.S.,Edwards, M.R.,Tsimbalyuk, S.,Vogel, O.A.,Smith, K.M.,Stewart, M.,Foster, J.K.,Bosence, L.A.,Aragao, D.,Roby, J.A.,Basler, C.F.,Forwood, J.K. MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13:1604-1604, 2022 Cited by PubMed: 35338144DOI: 10.1038/s41467-022-28851-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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