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8ECH
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BU of 8ech by Molmil
Tick-borne encephalitis virus capsid protein NLS bound to host importin alpha 2
Descriptor: Capsid protein C, Importin subunit alpha-1
Authors:Roby, J.A, Forwood, J.K.
Deposit date:2022-09-02
Release date:2022-09-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and biological functions of tick-borne encephalitis virus capsid protein
To Be Published
8FK3
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BU of 8fk3 by Molmil
Adeno-Associated Virus Porcine Origin capsid protein basic regions in complex with Importin-alpha 2
Descriptor: Importin subunit alpha-1, VP1
Authors:Hoad, M, Forwood, J.K, Roby, J.A.
Deposit date:2022-12-20
Release date:2023-03-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Characterization of Porcine Adeno-Associated Virus Capsid Protein with Nuclear Trafficking Protein Importin Alpha Reveals a Bipartite Nuclear Localization Signal.
Viruses, 15, 2023
8G4J
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BU of 8g4j by Molmil
Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state
Descriptor: Importin subunit alpha
Authors:Hawker, J.E, Roby, J.A, Stewart, M, Forwood, J.K.
Deposit date:2023-02-09
Release date:2023-02-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state
To Be Published
7RG1
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BU of 7rg1 by Molmil
Importin alpha2 in complex with MERS ORF4B H26A mutant
Descriptor: Importin subunit alpha-1, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Importin alpha2 in complex with MERS ORF4B NLS H26A mutant
To Be Published
7RG0
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BU of 7rg0 by Molmil
Importin alpha2 in complex with MERS ORF4B R24A mutant
Descriptor: Importin subunit alpha-1, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-07-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RFY
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BU of 7rfy by Molmil
Importin alpha3 in complex with MERS ORF4B
Descriptor: Importin subunit alpha-3, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-07-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RFX
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BU of 7rfx by Molmil
Importin alpha2 in complex with MERS ORF4B
Descriptor: Importin subunit alpha-1, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-07-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RFZ
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BU of 7rfz by Molmil
Importin alpha 2 in complex with MERS ORF4B NLS peptide
Descriptor: Importin subunit alpha-1, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-07-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RG2
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BU of 7rg2 by Molmil
Importin alpha2 in complex with MERS ORF4B R33A mutant
Descriptor: Importin subunit alpha-1, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-08-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RG3
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BU of 7rg3 by Molmil
Importin alpha2 in complex with MERS ORF4B R37A mutant
Descriptor: Importin subunit alpha-1, ORF4b
Authors:Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-08-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RG6
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BU of 7rg6 by Molmil
Importin alpha2 in complex with ORF4B Bat coronavirus HKU5
Descriptor: Importin subunit alpha-1, Non-structural protein ORF4b
Authors:Foster, J.K, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-08-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
8SG7
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BU of 8sg7 by Molmil
Adeno-Associated Virus Bat origin capsid protein basic regions in complex with importin-alpha 2
Descriptor: Importin subunit alpha-1, VP1 capsid
Authors:Hoad, M, Forwood, J.K.
Deposit date:2023-04-11
Release date:2023-07-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for nuclear import of bat adeno-associated virus capsid protein.
J.Gen.Virol., 105, 2024
7YWQ
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BU of 7ywq by Molmil
Solution structure of homodimeric Capsid protein (residues 17-95) of Tick-borne encephalitis virus (d16-TBEVC)
Descriptor: Genome polyprotein
Authors:Novotny, R.
Deposit date:2022-02-14
Release date:2022-10-19
Last modified:2022-11-23
Method:SOLUTION NMR
Cite:Tick-borne encephalitis virus capsid protein induces translational shutoff as revealed by its structural-biological analysis.
J.Biol.Chem., 298, 2022
8FUC
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BU of 8fuc by Molmil
Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2
Descriptor: Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein
Authors:Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
Deposit date:2023-01-17
Release date:2023-01-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
8FUA
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BU of 8fua by Molmil
Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein NLS1
Descriptor: Importin subunit alpha-1, Matrix protein
Authors:Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
Deposit date:2023-01-17
Release date:2023-02-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
8FUB
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BU of 8fub by Molmil
Crystal structure of human Importin alpha 3 in complex with Hendra virus matrix protein NLS1
Descriptor: Importin subunit alpha-3, Matrix protein
Authors:Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K.
Deposit date:2023-01-17
Release date:2023-02-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism.
Viruses, 15, 2023
8FWL
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BU of 8fwl by Molmil
Crystal structure of Australian bat lyssavirus nucleoprotein in complex with phosphoprotein chaperone
Descriptor: DI(HYDROXYETHYL)ETHER, Phosphoprotein,Nucleoprotein
Authors:Donnelly, C.M, Stewart, M, Forwood, J.K.
Deposit date:2023-01-23
Release date:2023-03-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex.
Viruses, 16, 2023
7RG4
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BU of 7rg4 by Molmil
Importin alpha2 in complex with p50 NLS
Descriptor: Importin subunit alpha-1, Isoform 3 of Nuclear factor NF-kappa-B p105 subunit
Authors:Smith, K.M, Tsimbalyuk, S, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-08-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
7RG5
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BU of 7rg5 by Molmil
Importin alpha3 in complex with p50 NLS
Descriptor: Importin subunit alpha-3, Isoform 3 of Nuclear factor NF-kappa-B p105 subunit
Authors:Smith, K.M, Tsimbalyuk, S, Aragao, D, Forwood, J.K.
Deposit date:2021-07-14
Release date:2021-08-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022

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PDB entries from 2024-04-24

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