PDB: 406 件ウェブページステータス検索Chemie searchBIRD

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8X85	Structure of leptin-LepR dimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor, ... 著者 Xie, Y.F, Shang, G.J, Qi, J.X, Gao, G.F. 登録日 2023-11-27 公開日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural plasticity of human leptin binding to its receptor LepR Hlife, 1, 2023
8X80	Structure of leptin-LepR trimer with a small gap 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, ... 著者 Xie, Y.F, Gao, G.F. 登録日 2023-11-27 公開日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Structural plasticity of human leptin binding to its receptor LepR Hlife, 1, 2023
7K7J	EphB6 receptor ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 6 著者 Goldgur, Y, Himanen, J. 登録日 2020-09-22 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.004 Å) 主引用文献 Structure of the EphB6 receptor ectodomain. Plos One, 16, 2021
3UP1	Crystal structure of the unliganded human interleukin-7 receptor extracellular domain 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 McElroy, C.A, Holland, P.J, Walsh, S.T.R. 登録日 2011-11-17 公開日 2012-02-08 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural reorganization of the interleukin-7 signaling complex. Proc.Natl.Acad.Sci.USA, 109, 2012
3UTO	Twitchin kinase region from C.elegans (Fn31-NL-kin-CRD-Ig26) 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... 著者 Castelmur, E, Barbieri, S, Mayans, O. 登録日 2011-11-26 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase. Proc.Natl.Acad.Sci.USA, 109, 2012
3FL7	Crystal structure of the human ephrin A2 ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ephrin receptor, ... 著者 Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2008-12-18 公開日 2009-01-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
7STI	Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-13 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STJ	Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1) 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-14 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STK	Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2) 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-14 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7STH	Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation 分子名称: Insulin, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-11-13 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
8GUY	human insulin receptor bound with two insulin molecules 分子名称: Insulin A chain, Insulin, isoform 2, ... 著者 Kim, J, Yunn, N, Ryu, S, Cho, Y. 登録日 2022-09-14 公開日 2022-11-09 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.18 Å) 主引用文献 Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
8G4L	Cryo-EM structure of the human cardiac myosin filament 分子名称: Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ... 著者 Dutta, D, Nguyen, V, Padron, R, Craig, R. 登録日 2023-02-10 公開日 2023-11-01 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Cryo-EM structure of the human cardiac myosin filament. Nature, 623, 2023
8FN8	Crystal structure of the C-terminal Fg domain of TNC with the single FN domain of PTPRZ 分子名称: CALCIUM ION, Receptor-type tyrosine-protein phosphatase zeta, Tenascin 著者 Bouyain, S. 登録日 2022-12-27 公開日 2023-07-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Protein-protein interactions between tenascin-R and RPTP zeta /phosphacan are critical to maintain the architecture of perineuronal nets. J.Biol.Chem., 299, 2023
8FN9	Crystal structure of the C-terminal Fg domain of TNR with the single FN domain of PTPRZ 分子名称: CALCIUM ION, Receptor-type tyrosine-protein phosphatase zeta, Tenascin-R 著者 Bouyain, S. 登録日 2022-12-27 公開日 2023-07-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Protein-protein interactions between tenascin-R and RPTP zeta /phosphacan are critical to maintain the architecture of perineuronal nets. J.Biol.Chem., 299, 2023
3DI2	Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain 分子名称: Interleukin-7, Interleukin-7 receptor subunit alpha, PENTAETHYLENE GLYCOL 著者 McElroy, C.A, Dohm, J.A, Walsh, S.T.R. 登録日 2008-06-19 公開日 2009-01-27 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex. Structure, 17, 2009
6BRB	Novel non-antibody protein scaffold targeting CD40L 分子名称: CD40 ligand, Tn3-like, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Oganesyan, V, Baca, M, Thisted, T, Grinberg, L, Wu, H, Dall'Acqua, W.F. 登録日 2017-11-30 公開日 2018-12-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity. Sci Transl Med, 11, 2019
3D1M	Crystal Structure of Sonic Hedgehog Bound to the third FNIII domain of CDO 分子名称: CALCIUM ION, Cell adhesion molecule, Sonic hedgehog protein, ... 著者 McLellan, J.S, Leahy, D.J. 登録日 2008-05-06 公開日 2008-09-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. Nature, 455, 2008
3DI3	Crystal structure of the complex of human interleukin-7 with glycosylated human interleukin-7 receptor alpha ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7, Interleukin-7 receptor subunit alpha 著者 McElroy, C.A, Dohm, J.A, Walsh, S.T.R. 登録日 2008-06-19 公開日 2009-01-27 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex. Structure, 17, 2009
6CE9	Insulin Receptor ectodomain in complex with two insulin molecules 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
3HHR	HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX 分子名称: HUMAN GROWTH HORMONE, HUMAN GROWTH HORMONE RECEPTOR (hGHbp) 著者 De Vos, A.M, Ultsch, M, Kossiakoff, A.A. 登録日 1993-12-30 公開日 1994-04-30 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science, 255, 1992
3F7P	Crystal structure of a complex between integrin beta4 and plectin 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 de Pereda, J.M. 登録日 2008-11-10 公開日 2009-03-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes Embo J., 28, 2009
6CEB	Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6CE7	Insulin Receptor ectodomain in complex with one insulin molecule 分子名称: Insulin A chain, Insulin B chain, Insulin receptor, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
3E0G	Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leukemia inhibitory factor receptor, ... 著者 Lupardus, P.J, Garcia, K.C. 登録日 2008-07-31 公開日 2008-09-23 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex. Mol.Cell, 31, 2008
5I99	Crystal structure of mouse CNTN3 Ig5-Fn2 domains 分子名称: Contactin-3, GLYCEROL 著者 Nikolaienko, R.M, Bouyain, S. 登録日 2016-02-19 公開日 2016-08-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues. J.Biol.Chem., 291, 2016

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