3HHR

HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX

Replaces:  2HHR

Summary for 3HHR

• Entry DOI: 10.2210/pdb3hhr/pdb
• Descriptor: HUMAN GROWTH HORMONE, HUMAN GROWTH HORMONE RECEPTOR (hGHbp) (2 entities in total)
• Functional Keywords: hormone/receptor, hormone-receptor complex
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01241; Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Growth hormone-binding protein: Secreted: P10912
• Total number of polymer chains: 3
• Total formula weight: 70012.83

Authors

De Vos, A.M.,Ultsch, M.,Kossiakoff, A.A. (deposition date: 1993-12-30, release date: 1994-04-30, Last modification date: 2011-07-13)

• Primary citation: de Vos, A.M.,Ultsch, M.,Kossiakoff, A.A.; Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.; Science, 255:306-312, 1992; PubMed: 1549776

Experimental method

X-RAY DIFFRACTION (2.8 Å)