3DI3

Crystal structure of the complex of human interleukin-7 with glycosylated human interleukin-7 receptor alpha ectodomain

Summary for 3DI3

• Entry DOI: 10.2210/pdb3di3/pdb
• Related: 3DI2
• Descriptor: Interleukin-7, Interleukin-7 receptor subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: interleukin, cytokine, cytokine receptor, ectodomain, glycoprotein, growth factor, secreted, disease mutation, membrane, phosphoprotein, receptor, scid, transmembrane, cytokine-cytokine receptor complex, cytokine/cytokine receptor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 44509.68

Authors

McElroy, C.A.,Dohm, J.A.,Walsh, S.T.R. (deposition date: 2008-06-19, release date: 2009-01-27, Last modification date: 2021-10-20)

• Primary citation: McElroy, C.A.,Dohm, J.A.,Walsh, S.T.; Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.; Structure, 17:54-65, 2009; PubMed: 19141282; DOI: 10.1016/j.str.2008.10.019

Experimental method

X-RAY DIFFRACTION (2.9 Å)