3D1M

Crystal Structure of Sonic Hedgehog Bound to the third FNIII domain of CDO

Summary for 3D1M

Entry DOI	10.2210/pdb3d1m/pdb
Descriptor	Sonic hedgehog protein, Cell adhesion molecule, ZINC ION, ... (5 entities in total)
Functional Keywords	fibronectin protein-protein complex, autocatalytic cleavage, developmental protein, glycoprotein, hydrolase, lipoprotein, membrane, palmitate, protease, secreted, immunoglobulin domain, transmembrane, signaling protein - cell adhesion complex, signaling protein / cell adhesion
Biological source	Mus musculus (Mouse) More
Cellular location	Sonic hedgehog protein C-product: Secreted, extracellular space . Sonic hedgehog protein N-product: Cell membrane ; Lipid-anchor : Q62226 Cell membrane ; Single-pass membrane protein : Q4KMG0
Total number of polymer chains	4
Total formula weight	61673.55
Authors	McLellan, J.S.,Leahy, D.J. (deposition date: 2008-05-06, release date: 2008-09-23, Last modification date: 2024-02-21)
Primary citation	McLellan, J.S.,Zheng, X.,Hauk, G.,Ghirlando, R.,Beachy, P.A.,Leahy, D.J. The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. Nature, 455:979-983, 2008 Cited by PubMed: 18794898 DOI: 10.1038/nature07358 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation