3D1M
Crystal Structure of Sonic Hedgehog Bound to the third FNIII domain of CDO
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sonic hedgehog protein | polymer | 168 | 19030.4 | 2 | UniProt (Q62226) Pfam (PF01085) | Mus musculus (Mouse) | SHH, HHG-1, Sonic hedgehog protein N-product, Sonic hedgehog protein C-product |
| 2 | C, D (C, D) | Cell adhesion molecule | polymer | 102 | 11660.8 | 2 | UniProt (Q4KMG0) Pfam (PF00041) | Homo sapiens (Human) | |
| 3 | E, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, G, I, J (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 189 (UniProt: Q62226)
C, D: 826 - 924 (UniProt: Q4KMG0)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Ser 25 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 823 | - | expression tag |
| Ser 824 | - | expression tag |
| Thr 825 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61382.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 291.1 | |
| All* | Total formula weight | 61673.5 |
