PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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5JY7	Complex of Mycobacterium smegmatis trehalose synthase with maltokinase 分子名称: CALCIUM ION, Maltokinase, Trehalose synthase/amylase TreS 著者 Futterer, K, Kermani, A.A, Besra, G.S. 登録日 2016-05-13 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Crystal structure of the TreS-Pep2 complex, initiating alpha-glucan synthesis in the GlgE pathway of mycobacteria. J.Biol.Chem., 2019
5K1J	Human TTR altered by a rhenium tris-carbonyl Pyta-C8 derivative 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Stura, E.A, Ciccone, L, Shepard, W. 登録日 2016-05-18 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Human TTR conformation altered by rhenium tris-carbonyl derivatives. J.Struct.Biol., 195, 2016
5JEI	Crystal structure of the GluA2 LBD in complex with FW 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ... 著者 Eibl, C, Salazar, H, Chebli, M, Plested, A.J.R. 登録日 2016-04-18 公開日 2017-02-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.229 Å) 主引用文献 Mechanism of partial agonism in AMPA-type glutamate receptors. Nat Commun, 8, 2017
5JFD	Thrombin in complex with (S)-N-(2-(aminomethyl)-5-chlorobenzyl)-1-((benzylsulfonyl)-D-arginyl)pyrrolidine-2-carboxamide 分子名称: (2S)-N-[[2-(aminomethyl)-5-chloro-phenyl]methyl]-1-[(2R)-5-carbamimidamido-2-(phenylmethylsulfonylamino)pentanoyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... 著者 Sandner, A, Heine, A, Klebe, G. 登録日 2016-04-19 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. J.Med.Chem., 62, 2019
5JGM	tRNA guanine Transglycosylase (TGT) in co-crystallized complex with ethyl (2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-6-yl)carbamate 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Ehrmann, F.R, Nguyen, D, Heine, A, Klebe, G. 登録日 2016-04-20 公開日 2017-05-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Carbamate-protected lin-Benzoguanines as promising candidates for improving solubility and membrane permeability To be Published
5JHO	Crystal structure of the regulatory domain of the sodium driven chloride bicarbonate exchanger. 分子名称: Electroneutral sodium bicarbonate exchanger 1 著者 Alvadia, C, Sommer, T, Bjerregaard-Andersen, K, Morth, J.P. 登録日 2016-04-21 公開日 2017-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger. Sci Rep, 7, 2017
5JHW	Crystal Structure of the GDF11:Follistatin 288 complex 分子名称: CITRATE ANION, Follistatin, Growth/differentiation factor 11, ... 著者 Walker, R.G, Thompson, T.B. 登録日 2016-04-21 公開日 2017-03-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for potency differences between GDF8 and GDF11. BMC Biol., 15, 2017
5JIA	The Crystal Structure Of IUS-SPRY Domain From RanBP10 分子名称: IMIDAZOLE, Ran-binding protein 10 著者 Hong, S.K, Kim, K.-H, Kim, E.E. 登録日 2016-04-22 公開日 2016-11-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. J.Mol.Biol., 428, 2016
5IZV	Crystal structure of the legionella pneumophila effector protein RavZ - F222 分子名称: Uncharacterized protein RavZ 著者 Kwon, D.H, Kim, L, Kim, B.-W, Hong, S.B, Song, H.K. 登録日 2016-03-26 公開日 2016-11-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.814 Å) 主引用文献 The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane Autophagy, 13, 2017
5IW0	Linked KDM5A Jmj Domain Bound to the Inhibitor N19 [2-(5-((4-chloro-2-methylbenzyl)oxy)-1H-pyrazol-1-yl)isonicotinic acid] 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 2-{5-[(4-chloro-2-methylphenyl)methoxy]-1H-pyrazol-1-yl}pyridine-4-carboxylic acid, ... 著者 Horton, J.R, Cheng, X. 登録日 2016-03-21 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chem Biol, 23, 2016
5IW7	Crystal structure of yeast Tsr1, a pre-40S ribosome synthesis factor 分子名称: Ribosome biogenesis protein TSR1,Ribosome biogenesis protein TSR1 著者 McCaughan, U.M, Jayachandran, U, Cook, A.G. 登録日 2016-03-22 公開日 2016-06-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases. Nat Commun, 7, 2016
5J2S	NKR-P1B from Rattus norvegicus 分子名称: Killer cell lectin-like receptor subfamily B member 1B allele A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Skalova, T, Vanek, O, Blaha, J, Duskova, J, Hasek, J, Koval, T, Dohnalek, J. 登録日 2016-03-30 公開日 2017-10-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of NKR-P1B from Rattus norvegicus To Be Published
5IGM	Crystal structure of the bromodomain of human BRD9 in complex with bromosporine (BSP) 分子名称: Bromodomain-containing protein 9, Bromosporine 著者 Tallant, C, Filippakopoulos, P, Picaud, S, Nunez-Alonso, G, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2016-02-28 公開日 2016-10-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Sci Adv, 2, 2016
5IH1	Macrolide 2'-phosphotransferase type II - complex with GDP and phosphorylated josamycin 分子名称: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Berghuis, A.M, Fong, D.H. 登録日 2016-02-28 公開日 2017-04-26 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure, 25, 2017
5I0I	Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Calmodulin, ... 著者 Isabet, T, Sweeney, H.L, Houdusse, A. 登録日 2016-02-04 公開日 2016-09-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
5I8M	Bicyclic antimibrocial peptides 分子名称: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, DLS-LYS-CYS-LYS-LEU-CYS-LEU-LYS-NH2, ... 著者 Di Bonaventura, I, Jin, X, Visini, R, Michaud, G, Robadey, M, Koehler, T, van Delden, C, Stocker, A, Darbre, T, Reymond, J.-L. 登録日 2016-02-19 公開日 2017-08-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms. Chem Sci, 8, 2017
5I90	Crystal Structure of PvdN from Pseudomonas Aeruginosa 分子名称: 1,2-ETHANEDIOL, PYRIDOXAL-5'-PHOSPHATE, PvdN 著者 Drake, E.J, Gulick, A.M. 登録日 2016-02-19 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.219 Å) 主引用文献 1.2 angstrom resolution crystal structure of the periplasmic aminotransferase PvdN from Pseudomonas aeruginosa. Acta Crystallogr F Struct Biol Commun, 72, 2016
5IA0	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with alisertib (MLN8237) 分子名称: 1,2-ETHANEDIOL, Ephrin type-A receptor 2, alisertib 著者 Kudlinzki, D, Linhard, V.L, Gande, S.L, Sreeramulu, S, Saxena, K, Heinzlmeir, S, Medard, G, Kuester, B, Schwalbe, H. 登録日 2016-02-21 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.948 Å) 主引用文献 Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs. ACS Chem. Biol., 11, 2016
5IB1	Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR measured at 295 K 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... 著者 Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. 登録日 2016-02-22 公開日 2017-02-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype. J.Biol.Chem., 2019
5IBD	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 24a 分子名称: 4-(3'-amino[1,1'-biphenyl]-3-yl)-3-(4-methoxyphenyl)-1H-pyrazol-5-amine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C. 登録日 2016-02-22 公開日 2016-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
5ID7	Crystal structure of human serum albumin in complex with phosphorodithioate derivative of myristoyl cyclic phosphatidic acid (cPA) 分子名称: (4S)-2-sulfanylidene-4-[(tetradecanoyloxy)methyl]-1,3,2lambda~5~-dioxaphospholane-2-thiolate, DI(HYDROXYETHYL)ETHER, Serum albumin, ... 著者 Sekula, B, Bujacz, A, Rytczak, P, Bujacz, G. 登録日 2016-02-24 公開日 2016-05-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic properties. Biosci.Rep., 36, 2016
5IJ8	Structure of the primary oncogenic mutant Y641N Hs/AcPRC2 in complex with a pyridone inhibitor 分子名称: 5,8-dichloro-2-[(4-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-({1-[(2R)-2-hydroxypropanoyl]piperidin-4-yl}oxy)-3,4-dihydroisoquinolin-1(2H)-one, Enhancer of Zeste Homolog 2 (EZH2),Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ... 著者 Gajiwala, K.S, Brooun, A, Deng, Y.-L, Liu, W. 登録日 2016-03-01 公開日 2016-05-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance. Nat Commun, 7, 2016
5IKN	Crystal Structure of the T7 Replisome in the Absence of DNA 分子名称: DNA primase/helicase, DNA-directed DNA polymerase, Thioredoxin-1 著者 Wallen, J.R, Ellenberger, T. 登録日 2016-03-03 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.802 Å) 主引用文献 Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome. Structure, 25, 2017
5IDU	Crystal structure of an acyl-CoA dehydrogenase domain protein from Burkholderia phymatum bound to FAD 分子名称: 1,2-ETHANEDIOL, Acyl-CoA dehydrogenase domain protein, FLAVIN-ADENINE DINUCLEOTIDE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Edwards, T.E. 登録日 2016-02-24 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of an acyl-CoA dehydrogenase domain protein from Burkholderia phymatum bound to FAD To Be Published
5IFE	Crystal structure of the human SF3b core complex 分子名称: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ... 著者 Cretu, C, Dybkov, O, De Laurentiis, E, Will, C.L, Luhrmann, R, Pena, V. 登録日 2016-02-25 公開日 2016-10-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations. Mol.Cell, 64, 2016

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