5JHW
Crystal Structure of the GDF11:Follistatin 288 complex
Summary for 5JHW
Entry DOI | 10.2210/pdb5jhw/pdb |
Related | 5JI1 |
Descriptor | Growth/differentiation factor 11, Follistatin, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | gdf11, follistatin, tgfbeta, ligand, cytokine-signaling protein complex, cytokine/signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 89735.64 |
Authors | Walker, R.G.,Thompson, T.B. (deposition date: 2016-04-21, release date: 2017-03-22, Last modification date: 2023-09-27) |
Primary citation | Walker, R.G.,Czepnik, M.,Goebel, E.J.,McCoy, J.C.,Vujic, A.,Cho, M.,Oh, J.,Aykul, S.,Walton, K.L.,Schang, G.,Bernard, D.J.,Hinck, A.P.,Harrison, C.A.,Martinez-Hackert, E.,Wagers, A.J.,Lee, R.T.,Thompson, T.B. Structural basis for potency differences between GDF8 and GDF11. BMC Biol., 15:19-19, 2017 Cited by PubMed: 28257634DOI: 10.1186/s12915-017-0350-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
Download full validation report