5I8M

Bicyclic antimibrocial peptides

Summary for 5I8M

Entry DOI	10.2210/pdb5i8m/pdb
Descriptor	Fucose-binding lectin, DLS-LYS-CYS-LYS-LEU-CYS-LEU-LYS-NH2, CALCIUM ION, ... (5 entities in total)
Functional Keywords	bicycle, antimicrobial peptide, pseudomonas aeruginosa, biofilm, sugar binding protein
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	5
Total formula weight	49132.63
Authors	Di Bonaventura, I.,Jin, X.,Visini, R.,Michaud, G.,Robadey, M.,Koehler, T.,van Delden, C.,Stocker, A.,Darbre, T.,Reymond, J.-L. (deposition date: 2016-02-19, release date: 2017-08-23, Last modification date: 2024-01-10)
Primary citation	Di Bonaventura, I.,Jin, X.,Visini, R.,Probst, D.,Javor, S.,Gan, B.H.,Michaud, G.,Natalello, A.,Doglia, S.M.,Kohler, T.,van Delden, C.,Stocker, A.,Darbre, T.,Reymond, J.L. Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms. Chem Sci, 8:6784-6798, 2017 Cited by PubMed: 29147502 DOI: 10.1039/c7sc01314k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.13 Å)

Structure validation