5ID7

Crystal structure of human serum albumin in complex with phosphorodithioate derivative of myristoyl cyclic phosphatidic acid (cPA)

Summary for 5ID7

Entry DOI	10.2210/pdb5id7/pdb
Descriptor	Serum albumin, (4S)-2-sulfanylidene-4-[(tetradecanoyloxy)methyl]-1,3,2lambda~5~-dioxaphospholane-2-thiolate, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	helical, three-domain protein, serum albumin, transport protein, drugs delivery, cyclic phosphatidic acid, lysophospholipid
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P02768
Total number of polymer chains	2
Total formula weight	136284.54
Authors	Sekula, B.,Bujacz, A.,Rytczak, P.,Bujacz, G. (deposition date: 2016-02-24, release date: 2016-05-11, Last modification date: 2024-01-10)
Primary citation	Sekula, B.,Ciesielska, A.,Rytczak, P.,Koziokiewicz, M.,Bujacz, A. Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic properties. Biosci.Rep., 36:-, 2016 Cited by PubMed: 27129297 DOI: 10.1042/BSR20160089 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation