5JGM

tRNA guanine Transglycosylase (TGT) in co-crystallized complex with ethyl (2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-6-yl)carbamate

Summary for 5JGM

• Entry DOI: 10.2210/pdb5jgm/pdb
• Related: 1P0D 3S1G 4KWO 4PUK 5I07
• Descriptor: Queuine tRNA-ribosyltransferase, GLYCEROL, ZINC ION, ... (7 entities in total)
• Functional Keywords: co-crystallization, shigellosis, prodrugs, transferase, transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
• Total number of polymer chains: 1
• Total formula weight: 43791.34

Authors

Ehrmann, F.R.,Nguyen, D.,Heine, A.,Klebe, G. (deposition date: 2016-04-20, release date: 2017-05-10, Last modification date: 2024-01-10)

• Primary citation: Ehrmann, F.R.,Hohn, C.,Heine, A.,Reuter, K.,Diederich, F.,Klebe, G.; Carbamate-protected lin-Benzoguanines as promising candidates for improving solubility and membrane permeability; To be Published,

Experimental method

X-RAY DIFFRACTION (1.38 Å)