5J03
 
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5JGO
 | | tRNA guanine Transglycosylase (TGT) in co-crystallized complex with allyl (2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-6-yl)carbamate | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | | 著者 | Ehrmann, F.R, Heine, A, Klebe, G. | | 登録日 | 2016-04-20 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Carbamate-protected lin-Benzoguanines as promising candidates for improving solubility and membrane permeability
To be published
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5IVE
 | | Linked KDM5A Jmj Domain Bound to the Inhibitor N8 ( 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile) | | 分子名称: | 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, MANGANESE (II) ION | | 著者 | Horton, J.R, Cheng, X. | | 登録日 | 2016-03-20 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.783 Å) | | 主引用文献 | Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.
Cell Chem Biol, 23, 2016
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5J5X
 | | Complex of PKA with the bisubstrate protein kinase inhibitor ARC-1416 | | 分子名称: | 4-(piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine, 47P-AZ1-DAL-DAR-DAR-DAR-DAR, SULFATE ION, ... | | 著者 | Alam, K.A, Ivan, T, Uri, A, Engh, R.A. | | 登録日 | 2016-04-04 | | 公開日 | 2016-07-20 | | 最終更新日 | 2019-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Bifunctional Ligands for Inhibition of Tight-Binding Protein-Protein Interactions.
Bioconjug.Chem., 27, 2016
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5J6Q
 | | Cwp8 from Clostridium difficile | | 分子名称: | CHLORIDE ION, Cell wall binding protein cwp8, SULFATE ION | | 著者 | Renko, M, Usenik, A, Turk, D. | | 登録日 | 2016-04-05 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The CWB2 Cell Wall-Anchoring Module Is Revealed by the Crystal Structures of the Clostridium difficile Cell Wall Proteins Cwp8 and Cwp6.
Structure, 25, 2017
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5J77
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5J8O
 | | Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor | | 分子名称: | (2R)-1-({3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)piperidine-2-carboxylic acid, Programmed cell death 1 ligand 1 | | 著者 | Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. | | 登録日 | 2016-04-08 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).
Oncotarget, 7, 2016
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5J92
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5J9O
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5J9U
 | | Crystal structure of the NuA4 core complex | | 分子名称: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
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5JGP
 | | Crystal structure of the nitrate/nitrite sensor NarQ fragment bound with iodide ions | | 分子名称: | IODIDE ION, NITRATE ION, Nitrate/nitrite sensor protein NarQ | | 著者 | Melnikov, I, Polovinkin, V, Popov, A, Gordeliy, V. | | 登録日 | 2016-04-20 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Fast iodide-SAD phasing for high-throughput membrane protein structure determination.
Sci Adv, 3, 2017
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5IZD
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5JMR
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5J25
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5IUY
 | | Structural insights of the outer-membrane channel OprN | | 分子名称: | CHLORIDE ION, FORMIC ACID, Multidrug efflux outer membrane protein OprN, ... | | 著者 | Ntsogo, Y, Garnier, C, Phan, G, Monlezun, L, Benas, P, Broutin, I. | | 登録日 | 2016-03-18 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Xenon for tunnelling analysis of the efflux pump component OprN.
PLoS ONE, 12, 2017
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5IVO
 | | BC2 nanobody | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BC2-nanobody | | 著者 | Braun, M.B, Stehle, T. | | 登録日 | 2016-03-21 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Peptides in headlock - a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy.
Sci Rep, 6, 2016
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5IX6
 | | X-ray structure of Auoxo3-encapsulated horse spleen apoferritin | | 分子名称: | CADMIUM ION, Ferritin light chain, GOLD ION, ... | | 著者 | Ferraro, G, Pontillo, N, Merlino, A. | | 登録日 | 2016-03-23 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Gold-based drug encapsulation within a ferritin nanocage: X-ray structure and biological evaluation as a potential anticancer agent of the Auoxo3-loaded protein.
Chem.Commun.(Camb.), 52, 2016
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5J89
 | | Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor | | 分子名称: | 1,2-ETHANEDIOL, N-{2-[({2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]pyridin-3-yl}methyl)amino]ethyl}acetamide, Programmed cell death 1 ligand 1 | | 著者 | Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. | | 登録日 | 2016-04-07 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).
Oncotarget, 7, 2016
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5J8S
 | | Iron-free state of Rana Catesbeiana H' ferritin variant E57A/E136A/D140A | | 分子名称: | CHLORIDE ION, Ferritin, middle subunit, ... | | 著者 | Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P. | | 登録日 | 2016-04-08 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016
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5J9N
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5J9V
 | | Ten minutes iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A | | 分子名称: | CHLORIDE ION, FE (II) ION, Ferritin, ... | | 著者 | Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity.
Chemistry, 22, 2016
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5IXC
 | | Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate | | 分子名称: | BARIUM ION, Cytosolic phospholipase A2 delta, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate | | 著者 | Wang, H, Klein, M.G. | | 登録日 | 2016-03-23 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition.
J.Mol.Biol., 428, 2016
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5JFT
 | | Zebra Fish Caspase-3 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACE-ASP-GLU-VAL-ASK, ... | | 著者 | Tucker, M.B, MacKenzie, S.H, Maciag, J.J, Dirscherl, H, Swartz, P.D, Yoder, J.A, Hamilton, P.T, Clark, A.C. | | 登録日 | 2016-04-19 | | 公開日 | 2016-10-26 | | 最終更新日 | 2016-11-02 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish.
Protein Sci., 25, 2016
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5J5O
 | | Translation initiation factor 4E in complex with m7GppppG mRNA 5' cap analog | | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]-7-methylguanosine, Eukaryotic translation initiation factor 4E, GLYCEROL | | 著者 | Warminski, M, Nowak, E, Rydzik, A.M, Kowalska, J, Jemielity, J, Nowotny, M. | | 登録日 | 2016-04-03 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.867 Å) | | 主引用文献 | mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.
Nucleic Acids Res., 45, 2017
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5JIE
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